ArticleJournal of vision2017
Neuronal mechanisms underlying differences in spatial resolution between darks and lights in human vision.
Article in Journal of vision, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed.
- Human accommodative visuomotor function is driven by contrast through ON and OFF pathways and is enhanced in myopia.Cell reports · 2026Article
- The Effect of Contrast Reversal on Peripheral Visual Acuity.Translational vision science & technology · 2025Article
- Relative Role of ON/OFF Pathways in Resolving and Adapting to Blur in Myopes and Emmetropes.Investigative ophthalmology & visual science · 2025Article
- Article
- The relationship between ON-OFF function and OCT structural and angiographic parameters in early diabetic retinal disease.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Impact of Glaucomatous Ganglion Cell Damage on Central Visual Function.Annual review of vision science · 2024Review
- A virtual patient simulation modeling the neural and perceptual effects of human visual cortical stimulation, from pulse trains to percepts.Scientific reports · 2024Article
- Contrast Sensitivity of ON and OFF Human Retinal Pathways in Myopia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Differences in visual stimulation between reading and walking and implications for myopia development.Journal of vision · 2023Article
- Luminance Contrast Shifts Dominance Balance between ON and OFF Pathways in Human Vision.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Cortical mechanisms of visual brightness.Cell reports · 2022Article
- Personalizing image enhancement for critical visual tasks: improved legibility of papyri using color processing and visual illusions.International journal on document analysis and recognition (Online) · 2022Article
- ON and OFF Signaling Pathways in the Retina and the Visual System.Frontiers in ophthalmology · 2022Article
- Article
- Image luminance changes contrast sensitivity in visual cortex.Cell reports · 2021Article
- Ambient Light Regulates Retinal Dopamine Signaling and Myopia Susceptibility.Investigative ophthalmology & visual science · 2021Article
- Amblyopia Affects the ON Visual Pathway More than the OFF.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Functional Specialization of ON and OFF Cortical Pathways for Global-Slow and Local-Fast Vision.Cell reports · 2019Article
- Cortical Balance Between ON and OFF Visual Responses Is Modulated by the Spatial Properties of the Visual Stimulus.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Pathway-Specific Asymmetries between ON and OFF Visual Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Artists and astronomers noticed centuries ago that humans perceive dark features in an image differently from light ones; however, the neuronal mechanisms underlying these dark/light asymmetries remained unknown. Based on computational modeling of neuronal responses, we have previously proposed that such perceptual dark/light asymmetries originate from a luminance/response saturation within the ON retinal pathway. Consistent with this prediction, here we show that stimulus conditions that increase ON luminance/response saturation (e.g., dark backgrounds) or its effect on light stimuli (e.g., optical blur) impair the perceptual discrimination and salience of light targets more than dark targets in human vision. We also show that, in cat visual cortex, the magnitude of the ON luminance/response saturation remains relatively constant under a wide range of luminance conditions that are common indoors, and only shifts away from the lowest luminance contrasts under low mesopic light. Finally, we show that the ON luminance/response saturation affects visual salience mostly when the high spatial frequencies of the image are reduced by poor illumination or optical blur. Because both low luminance and optical blur are risk factors in myopia, our results suggest a possible neuronal mechanism linking myopia progression with the function of the ON visual pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.