Evidence map›Paper›PMID 29196711›Full record

ArticleScientific reports2017

The Uniform Pattern of Growth and Skeletal Maturation during the Human Adolescent Growth Spurt.

James O Sanders, Xing Qiu, Xiang Lu, Dana L Duren, Raymond W Liu, Debbie Dang, Mariano E Menendez, Sarah D Hans, David R Weber, Daniel R Cooperman

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed.

  1. Article
  2. Kyphosis, lordosis and height velocity. What is the effect of rate of growth on the development of the sagittal parameters of the spine in normal children?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  19. A comparative analysis of axial and appendicular skeletal maturity staging systems through assessment of longitudinal growth and curve modulation after VBT surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  20. Pediatric spinal alignment and spinal development.North American Spine Society journal · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

James O SandersDepartment of Orthopaedics and Rehabilitation, University of Rochester, Rochester, New York, USA. james_sanders@urmc.rochester.edu.ORCID 0000-0001-7897-4161
Xing QiuDepartment of Biostatistics and Computational Biology, University of Rochester, Rochester, New York, USA.ORCID 0000-0002-2330-3544
Xiang LuDepartment of Biostatistics and Computational Biology, University of Rochester, Rochester, New York, USA.
Dana L DurenDepartment of Orthopaedic Surgery, University of Missouri, Columbia, USA.
Raymond W LiuDepartment of Orthopaedic Surgery, Case Western Reserve University, Cleveland, Ohio, USA.
Debbie DangDepartment of Orthopaedic Surgery, University of California San Francisco, California, USA.
Mariano E MenendezDepartment of Orthopedics, Tufts University School of Medicine, Boston, Massachusetts, USA.
Sarah D HansColon Rectal Specialists, Rochester Hills, Michigan, USA.
David R WeberDepartment of Pediatrics, University of Rochester, Rochester, New York, USA.
Daniel R CoopermanDepartment of Orthopaedics and Rehabilitation, Yale University, New Haven, Connecticut, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Translational Molecular Pediatric ResearchK12HD068373 · NICHD · UNIVERSITY OF ROCHESTER · PI SCHOR, NINA F · 2011 to 2015
$2.0M
NCATS NIH HHS UL1 TR001863NICHD NIH HHS K12 HD068373
6 · The paper itself

Abstract

Humans are one of the few species undergoing an adolescent growth spurt. Because children enter the spurt at different ages making age a poor maturity measure, longitudinal studies are necessary to identify the growth patterns and identify commonalities in adolescent growth. The standard maturity determinant, peak height velocity (PHV) timing, is difficult to estimate in individuals due to diurnal, postural, and measurement variation. Using prospective longitudinal populations of healthy children from two North American populations, we compared the timing of the adolescent growth spurt's peak height velocity to normalized heights and hand skeletal maturity radiographs. We found that in healthy children, the adolescent growth spurt is standardized at 90% of final height with similar patterns for children of both sexes beginning at the initiation of the growth spurt. Once children enter the growth spurt, their growth pattern is consistent between children with peak growth at 90% of final height and skeletal maturity closely reflecting growth remaining. This ability to use 90% of final height as easily identified important maturity standard with its close relationship to skeletal maturity represents a significant advance allowing accurate prediction of future growth for individual children and accurate maturity comparisons for future studies of children's growth.

Indexed as

AdolescentBody HeightChildChild, PreschoolFemaleHumansInfantMaleProspective StudiesSkeleton

Identifiers

PMID29196711
PMCPMC5711808

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.