ArticleScientific reports2017
Medical examination powers miR-194-5p as a biomarker for postmenopausal osteoporosis.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dysregulation of MicroRNAs in Hypertrophy and Ossification of Ligamentum Flavum: New Advances, Challenges, and Potential Directions.Frontiers in genetics · 2021Pooled it
- Artificial Intelligence for Osteoporosis Diagnosis, Risk Prediction and Therapy: Current Advances, Clinical Challenges, and Future Perspectives.Clinical interventions in aging · 2026Review
- MiR-23a-5p affects postmenopausal osteoporosis by targeting ALX3 to regulate osteoblast differentiation.Journal of orthopaedic surgery and research · 2025Article
- Article
- Inhibition of miR-194-5p avoids DUSP9 downregulation thus limiting sepsis-induced cardiomyopathy.Scientific reports · 2024Article
- Circulating and extracellular vesicle-derived microRNAs as biomarkers in bone-related diseases.Frontiers in endocrinology · 2023Review
- FOXO4 May Be a Biomarker of Postmenopausal Osteoporosis.International journal of general medicine · 2022Article
- A systematic review of miRNAs as biomarkers in osteoporosis disease.Journal of diabetes and metabolic disorders · 2021Article
- Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Silencing of miR-483-5p alleviates postmenopausal osteoporosis by targeting SATB2 and PI3K/AKT pathway.Aging · 2021Article
- Identification of Potential Therapeutic Targets and Molecular Regulatory Mechanisms for Osteoporosis by Bioinformatics Methods.BioMed research international · 2021Article
- Inhibition of Circulating miR-194-5p Reverses Osteoporosis through Wnt5a/β-Catenin-Dependent Induction of Osteogenic Differentiation.Molecular therapy. Nucleic acids · 2020Article
- Non-Coding RNAs as Potential Novel Biomarkers for Early Diagnosis of Hepatic Insulin Resistance.International journal of molecular sciences · 2020Review
- MicroRNA and Human Bone Health.JBMR plus · 2019Review
- Article
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Authors and funding
11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
An important attribute of microRNAs is their potential use as disease biomarkers. However, such applications may be restricted because of unsatisfactory performance of the microRNA of interest. Owing to moderate correlation with spine T-score, miR-194-5p was identified as a potential biomarker for postmenopausal osteoporosis. Here, we determined whether medical examination could improve its characteristic as a biomarker for postmenopausal osteoporosis. We recruited 230 postmenopausal Chinese women to measure circulating levels of miR-194-5p, determine the spine bone status, and perform a 42-item medical examination. No obvious information redundancy was observed between miR-194-5p and any one item. However, on examining miR-194-5p alone, the sensitivity at fixed specificity of 0.9 (SE
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