Evidence map›Paper›PMID 29196536›Full record

ArticleGenes & development2017

Novel transcriptional networks regulated by CLOCK in human neurons.

Miles R Fontenot, Stefano Berto, Yuxiang Liu, Gordon Werthmann, Connor Douglas, Noriyoshi Usui, Kelly Gleason, Carol A Tamminga, Joseph S Takahashi, Genevieve Konopka

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  4. Article
  5. Article
  6. Exome Sequencing in an ADSHE Family: VUS Identification and Limits.International journal of environmental research and public health · 2022
    Article
  7. Review
  8. Review
  9. Article
  10. The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions.International journal of molecular sciences · 2021
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Genes · 2019
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Miles R FontenotDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Stefano BertoDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Yuxiang LiuDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Gordon WerthmannDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Connor DouglasDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Noriyoshi UsuiDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Kelly GleasonDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Carol A TammingaDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Joseph S TakahashiDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Genevieve KonopkaDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
The University of Texas Southwestern Medical Center · USSouthwestern Medical Center · US

Funding

Human Specific Brain DNA Methylation and Neuropsychiatric DiseasesR01MH103517 · NIMH · GEORGIA INSTITUTE OF TECHNOLOGY · PI JORDAN, IRVING KING, PREUSS, TODD M · 2015 to 2019
$3.5M
Identification of human-relevant CLOCK molecular signaling pathwaysR21MH107672 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI KONOPKA, GENEVIEVE · 2015 to 2016
$445k
Neocortical regulation of circadian rhythmsF30MH105158 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI FONTENOT, MILES · 2015 to 2018
$135k
NIMH NIH HHS F30 MH105158NIMH NIH HHS R01 MH103517NIMH NIH HHS R21 MH107672
6 · The paper itself

Abstract

The molecular mechanisms underlying human brain evolution are not fully understood; however, previous work suggested that expression of the transcription factor

Indexed as

Cell LineCell MovementCLOCK ProteinsEpigenesis, GeneticGene Expression Regulation, DevelopmentalGene Knockdown TechniquesGene Regulatory NetworksHumansNeocortexNeurodevelopmental DisordersNeuronsCLOCK Proteinscircadian rhythmsevolutionhuman brainneurogenomicsneuronal migration

Identifiers

PMID29196536
PMCPMC5749161
OpenAlexW2774098908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.