ArticleJournal of immunology (Baltimore, Md. : 1950)2018
Integrin α
Open access · bronzeAbstract read
In one paragraph
Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals.Science translational medicine · 2018Trial
- α4 Integrin blockade impairs CD8+ T cell neuroimmune surveillance following SIV infection.The Journal of clinical investigation · 2026Article
- Comparative analysis of human gut- and blood-derived mononuclear cells: contrasts in function and phenotype.Frontiers in immunology · 2024Article
- Review
- Blocking αScience translational medicine · 2021Article
- Mucosal integrin α4β7 blockade fails to reduce the seeding and size of viral reservoirs in SIV-infected rhesus macaques.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.Frontiers in immunology · 2020Article
- Evaluation of an antibody to αScience (New York, N.Y.) · 2019Article
- Blocking αScience (New York, N.Y.) · 2019Article
- Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques.PLoS pathogens · 2019Article
- Vedolizumab-mediated integrin α4β7 blockade does not control HIV-1SF162 rebound after combination antiretroviral therapy interruption in humanized mice.AIDS (London, England) · 2019Article
- γδ T-cell responses during HIV infection and antiretroviral therapy.Clinical & translational immunology · 2019Review
- Comparison of the integrin α4β7 expression pattern of memory T cell subsets in HIV infection and ulcerative colitis.PloS one · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 8 institutions in 2 countries.
Giulia CalendaCenter for Biomedical Research, Population Council, New York, NY 10065.
Rassamon KeawvichitDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322.ORCID 0000-0002-7922-444X
Géraldine Arrode-BrusésCenter for Biomedical Research, Population Council, New York, NY 10065.
Kovit PattanapanyasatDepartment of Immunology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.ORCID 0000-0003-1037-6610
Ines FrankCenter for Biomedical Research, Population Council, New York, NY 10065.
Siddappa N ByrareddyDepartment of Pharmacology and Experimental Neurosciences, University of Nebraska Medical Center, Omaha, NE 68198.ORCID 0000-0002-6889-4640
James ArthosLaboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
Claudia CicalaLaboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-1181-8997
Brooke GraspergeTulane National Primate Research Center, Tulane University, Covington, LA 70433.ORCID 0000-0002-1262-6217
James L BlanchardTulane National Primate Research Center, Tulane University, Covington, LA 70433.
Agegnehu GettieAaron Diamond AIDS Research Center, Rockefeller University, New York, NY 10016; and.
Keith A ReimannMassBiologics, University of Massachusetts Medical School, Boston, MA 02126.ORCID 0000-0003-3074-6500
Aftab A AnsariDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322; emartinelli@popcouncil.org pathaaa@emory.edu.ORCID 0000-0003-4607-7268
Elena MartinelliCenter for Biomedical Research, Population Council, New York, NY 10065; emartinelli@popcouncil.org pathaaa@emory.edu.ORCID 0000-0002-3416-9627
Population Council · USNational Institutes of Health · USSiriraj Hospital · THTulane University · USAaron Diamond AIDS Research Center · USEmory University · USUniversity of Massachusetts Chan Medical School · USUniversity of Nebraska Medical Center · US
Funding
Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4MNonhuman Primate Reagent ResourceU24AI126683 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Diogo Magnani · 2016 to 2026
$20.1MRole of HIV Envelope Proteins In Viral Replication and HIV PathogenesisZIAAI000887 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CICALA, CLAUDIA · 2009 to 2025
$15.2MInteraction of HIV envelope with cell surface receptorsZIAAI000883 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ARTHOS, JAMES L · 2009 to 2024
$14.0MGut Homing Cells in SIV infectionR01AI098628 · NIAID · EMORY UNIVERSITY · PI ANSARI, AFTAB A. · 2012 to 2016
$7.0MResource for Nonhuman Primate Cell Depleting AntibodiesR24OD010976 · OD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ENGELMAN, KATHLEEN, MAGNANI, DIOGO · 2012 to 2019
$4.7MRole of integrins in HIV/SIV transmission across cervico-vaginal mucosaR01AI098546 · NIAID · POPULATION COUNCIL · PI MARTINELLI, ELENA · 2012 to 2016
$3.9MAnti-angiogenic actions of taxotereR01CA098456 · NCI · MONTEFIORE MEDICAL CENTER (BRONX, NY) · PI SCHWARTZ, EDWARD L · 2003 to 2007
$1.3MRole of integrin a4b7 in HIV/SIV transmission across cervico-vaginal mucosaR56AI098546 · NIAID · POPULATION COUNCIL · PI MARTINELLI, ELENA · 2017 to 2017
$953kNCI NIH HHS R01 CA098456NIAID NIH HHS R01 AI098546NIAID NIH HHS R01 AI098628NIAID NIH HHS R56 AI098546NIAID NIH HHS U24 AI126683NIH HHS P51 OD011104NIH HHS R24 OD010976
Abstract
Infusion of a simianized anti-α
Indexed as
Lymphocyte CountAnimalsCD4-Positive T-LymphocytesDendritic CellsFemaleIntegrinsLymphocyte SubsetsMacaca mulattaMucous MembraneOrgan SpecificityReceptors, CCR6integrin alpha4beta7IntegrinsReceptors, CCR6
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.