Evidence map›Paper›PMID 29196450›Full record

ArticleScience immunology2017

Migratory CD11b

Jayendra Kumar Krishnaswamy, Uthaman Gowthaman, Biyan Zhang, Johan Mattsson, Louis Szeponik, Dong Liu, Renee Wu, Theresa White, Samuele Calabro, Lan Xu and 10 more

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
160citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

160 citing papers in PubMed, 1 synthesis or guideline pooled it, 223 citations in OpenAlex.

  1. Mucosal immunity and vaccine development.Signal transduction and targeted therapy · 2026
    Pooled it
  2. Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Extrafollicular and other non-germinal center B cell responses.Journal of immunology (Baltimore, Md. : 1950) · 2026
    Review
  13. Review
  14. Defining the Role of Dendritic Cells in Red Blood Cell Alloimmunization.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  15. Article
  16. Article
  17. Review
  18. T follicular helper cell development during malaria.Current opinion in immunology · 2025
    Review
  19. Article
  20. Article

100 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 4 countries.

Jayendra Kumar KrishnaswamyDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.
Uthaman GowthamanDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.
Biyan ZhangDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0003-0329-2451
Johan MattssonBioscience, Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca, 431 50 Mölndal, Sweden.
Louis SzeponikDepartment of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0002-8627-6969
Dong LiuDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.
Renee WuDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-9521-1657
Theresa WhiteDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0001-8166-6004
Samuele CalabroDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0001-7881-5160
Lan XuDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-9909-7660
Magalie A ColletJackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.ORCID 0000-0002-7200-345X
Marina YurievaJackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.ORCID 0000-0002-5761-0382
Samuel AlsénDepartment of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, 405 30 Gothenburg, Sweden.
Per FogelstrandDepartment of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, 413 45 Gothenburg, Sweden.
Anne WalterDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Victoria 3000, Australia.ORCID 0000-0003-2179-9272
William R HeathDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Victoria 3000, Australia.ORCID 0000-0001-9670-259X
Scott N MuellerDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Victoria 3000, Australia.ORCID 0000-0002-3838-3989
Ulf YrlidDepartment of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0002-3431-6770
Adam WilliamsJackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA. stephanie.eisenbarth@yale.edu adam.williams@jax.org.ORCID 0000-0002-5151-4103
Stephanie C EisenbarthDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA. stephanie.eisenbarth@yale.edu adam.williams@jax.org.ORCID 0000-0002-1244-208X
Yale University · USUniversity of Gothenburg · SEAustralian Research Council · AUJackson Laboratory · USAstraZeneca (Sweden) · SERoche (Switzerland) · CHWashington University in St. Louis · US

Funding

Regulation of adaptive immunity by the NOD-like receptor NLRP10R01AI108829 · NIAID · YALE UNIVERSITY · PI EISENBARTH, STEPHANIE CAROLINE · 2014 to 2018
$2.1M
Identifying lincRNAs critical in asthma pathogenesisR21AI110776 · NIAID · YALE UNIVERSITY · PI FLAVELL, RICHARD A, WILLIAMS, ADAM · 2014 to 2015
$458k
NIAID NIH HHS R01 AI108829NIAID NIH HHS R21 AI110776
6 · The paper itself

Abstract

T follicular helper (Tfh) cells are a subset of CD4

Indexed as

AnimalsAntibodiesBasic-Leucine Zipper Transcription FactorsCD11b AntigenCell ProliferationDendritic CellsFemaleMaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicRepressor ProteinsT-Lymphocytes, Helper-InducerAntibodiesBasic-Leucine Zipper Transcription FactorsCD11b AntigenRepressor ProteinsSNFT protein, mouse

Identifiers

PMID29196450
PMCPMC7847246
OpenAlexW2771277947

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.