Evidence map›Paper›PMID 29196322›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

A New, High-Efficacy, Noninvasive Transcranial Electric Stimulation Tuned to Local Neurodynamics.

Carlo Cottone, Andrea Cancelli, Patrizio Pasqualetti, Camillo Porcaro, Carlo Salustri, Franca Tecchio

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Sensorimotor Interaction Against Trauma.Frontiers in neuroscience · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlo CottoneLaboratory of Electrophysiology for Translational NeuroScience, Institute of Cognitive Sciences and Technologies, Consiglio Nazionale delle Ricerche, Rome, I-00185 Italy.ORCID 0000-0002-0262-1551
Andrea CancelliLaboratory of Electrophysiology for Translational NeuroScience, Institute of Cognitive Sciences and Technologies, Consiglio Nazionale delle Ricerche, Rome, I-00185 Italy.
Patrizio PasqualettiService of Medical Statistics and Information Technology, Fatebenefratelli Foundation for Health Research and Education, AFaR Division, Rome, 00186 Italy.ORCID 0000-0001-5560-1979
Camillo PorcaroLaboratory of Electrophysiology for Translational NeuroScience, Institute of Cognitive Sciences and Technologies, Consiglio Nazionale delle Ricerche, Rome, I-00185 Italy.
Carlo SalustriLaboratory of Electrophysiology for Translational NeuroScience, Institute of Cognitive Sciences and Technologies, Consiglio Nazionale delle Ricerche, Rome, I-00185 Italy.
Franca TecchioLaboratory of Electrophysiology for Translational NeuroScience, Institute of Cognitive Sciences and Technologies, Consiglio Nazionale delle Ricerche, Rome, I-00185 Italy, franca.tecchio@cnr.it.ORCID 0000-0002-1325-5059

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, we pose the following working hypothesis: in humans, transcranial electric stimulation (tES) with a time course that mimics the endogenous activity of its target is capable of altering the target's excitability. In our case, the target was the primary motor cortex (M1). We identified the endogenous neurodynamics of hand M1's subgroups of pyramidal neuronal pools in each of our subjects by applying Functional Source Separation (FSS) to their EEG recordings. We then tested whether the corticospinal excitability of the hand representation under the above described stimulation, which we named transcranial individual neurodynamics stimulation (tIDS), was higher than in the absence of stimulation (baseline). As a check, we compared tIDS with the most efficient noninvasive facilitatory corticospinal tES known so far, which is 20 Hz transcranial alternating current stimulation (tACS). The control conditions were as follows: (1) sham, (2) transcranial random noise stimulation (tRNS) in the same frequency range as tIDS (1-250 Hz), and (3) a low current tIDS (tIDS

Indexed as

AdultElectroencephalographyEvoked Potentials, MotorFemaleHumansMaleMiddle AgedMotor CortexPyramidal CellsTranscranial Direct Current StimulationYoung AdultEEGFunctional Source Separation (FSS)personal/individual dynamics of neuronal activityprimary motor areatranscranial electric stimulationtranscranial individual neurodynamics stimulation

Identifiers

PMID29196322
PMCPMC6596189

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.