Evidence map›Paper›PMID 29195915›Full record

ArticleInternational journal of pharmaceutics2018

Development and in-vitro characterization of nanoemulsions loaded with paclitaxel/γ-tocotrienol lipid conjugates.

Ahmed Abu-Fayyad, Mohammad M Kamal, Jennifer L Carroll, Ana-Maria Dragoi, Robert Cody, James Cardelli, Sami Nazzal

Abstract read
In one paragraph

Article in International journal of pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ahmed Abu-FayyadCollege of Health and Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, LA, USA; Modavar Pharmaceuticals, Washington, DC, USA.
Mohammad M KamalCollege of Health and Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, LA, USA.
Jennifer L CarrollFeist-Weiller Cancer Center, Innovative Northwest Louisiana Experimental Therapeutics (INLET), Louisiana State University Health Sciences Center, Shreveport, LA, USA.
Ana-Maria DragoiFeist-Weiller Cancer Center, Innovative Northwest Louisiana Experimental Therapeutics (INLET), Louisiana State University Health Sciences Center, Shreveport, LA, USA; Department of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, USA.
Robert CodyJEOL USA, Inc., Peabody, MA, USA.
James CardelliSegue Therapeutics, Shreveport, LA, USA.
Sami NazzalCollege of Health and Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, LA, USA. Electronic address: nazzal@ulm.edu.
University of Louisiana at Monroe · USLouisiana State University Health Sciences Center Shreveport · USJEOL (United States) · US

Funding

STABILITY' (symptomatic review during biologic therapy) Review in Inflammatory Bowel DiseaseP20GM103424 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI Konstantin G Kousoulas · 2012 to 2026
$57.4M
NIGMS NIH HHS P20 GM103424
6 · The paper itself

Abstract

Vitamin E TPGS is a tocopherol (α-T) based nonionic surfactant that was used in the formulation of the Tocosol™ paclitaxel nanoemulsion, which was withdrawn from phase III clinical trials. Unlike tocopherols, however, the tocotrienol (T

Indexed as

Antineoplastic AgentsCell Line, TumorChemistry, PharmaceuticalEmulsionsHumansLipidsNanoparticlesPaclitaxelPolyethylene GlycolsTocotrienolsVitamin EAntineoplastic AgentsEmulsionsLipidsPaclitaxelPolyethylene GlycolstocophersolanTocotrienolsVitamin ECancer chemotherapyDrug deliveryNanoemulsionNanotechnologyPaclitaxelPEGylationTocotrienolVitamin E TPGS

Identifiers

PMID29195915
PMCPMC5803428
OpenAlexW2771263811

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.