Evidence map›Paper›PMID 29195756›Full record

ArticleUltrasound in medicine & biology2018

An Ultrasound Surface Wave Technique for Assessing Skin and Lung Diseases.

Xiaoming Zhang, Boran Zhou, Sanjay Kalra, Brian Bartholmai, James Greenleaf, Thomas Osborn

Abstract read
In one paragraph

Article in Ultrasound in medicine & biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Interventional Ultrasound in Dermatology: A Pictorial Overview Focusing on Cutaneous Melanoma Patients.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Effect of a Thin Fluid Layer on Surface Wave Speed Measurements: A Lung Phantom Study.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiaoming ZhangDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA. Electronic address: zhang.xiaoming@mayo.edu.
Boran ZhouDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Sanjay KalraDepartment of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Brian BartholmaiDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
James GreenleafDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Thomas OsbornDepartment of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA.
Mayo Clinic · USWinnMed · US

Funding

Measurement of surface lung tissue using ultrasoundR01HL125234 · NHLBI · MAYO CLINIC ROCHESTER · PI ZHANG, XIAOMING · 2015 to 2018
$1.5M
NHLBI NIH HHS R01 HL125234
6 · The paper itself

Abstract

Systemic sclerosis (SSc) is a multi-organ connective tissue disease characterized by immune dysregulation and organ fibrosis. Severe organ involvement, especially of the skin and lung, is the cause of morbidity and mortality in SSc. Interstitial lung disease (ILD) includes multiple lung disorders in which the lung tissue is fibrotic and stiffened. The purpose of this study was to translate ultrasound surface wave elastography (USWE) for assessing patients with SSc and/or ILD via measuring surface wave speeds of both skin and superficial lung tissue. Forty-one patients with both SSc and ILD and 30 healthy patients were enrolled in this study. An external harmonic vibration was used to generate the wave propagation on the skin or lung. Three excitation frequencies of 100, 150 and 200 Hz were used. An ultrasound probe was used to measure the wave propagation in the tissue non-invasively. Surface wave speeds were measured on the forearm and upper arm of both left and right arm, as well as the upper and lower lungs, through six intercostal spaces of patients and healthy patients. Viscoelasticity of the skin was calculated by the wave speed dispersion with frequency using the Voigt model. The magnitudes of surface wave speed and viscoelasticity of patients' skin were significantly higher than those of healthy patients (p <0.0001) for each location and each frequency. The surface wave speeds of patients' lung were significantly higher than those of healthy patients (p <0.0001) for each location and each frequency. USWE is a non-invasive and non-ionizing technique for measuring both skin and lung surface wave speed and may be useful for quantitative assessment of SSc and/or ILD.

Indexed as

AdultAgedAged, 80 and overElasticity Imaging TechniquesFemaleHumansLungLung Diseases, InterstitialMaleMiddle AgedScleroderma, SystemicSkinInterstitial lung diseaseLungSclerodermaSkinUltrasound surface wave elastography

Identifiers

PMID29195756
PMCPMC5743597
OpenAlexW2772332333

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.