Evidence map›Paper›PMID 29194868›Full record

ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2018

Narrowing filtered QRS duration on signal-averaged electrocardiogram predicts outcomes in cardiac resynchronization therapy patients with nonischemic heart failure.

Atsushi Suzuki, Tsuyoshi Shiga, Daigo Yagishita, Yoshimi Yagishita-Tagawa, Kotaro Arai, Yuji Iwanami, Koichiro Ejima, Kyomi Ashihara, Morio Shoda, Nobuhisa Hagiwara

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In one paragraph

Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Narrowing filtered QRS duration on signal-averaged electrocardiogram predicts outcomes in cardiac resynchronization therapy patients with nonischemic heart failure.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Atsushi SuzukiDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Tsuyoshi ShigaDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.ORCID 0000-0003-0358-7196
Daigo YagishitaDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Yoshimi Yagishita-TagawaDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Kotaro AraiDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Yuji IwanamiDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Koichiro EjimaDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Kyomi AshiharaDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Morio ShodaClinical Research Division for Heart Rhythm Management, Tokyo Women's Medical University, Tokyo, Japan.
Nobuhisa HagiwaraDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Tokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the impact of changes in the filtered QRS duration (fQRS) on signal-averaged electrocardiograms (SAECGs) from pre- to postimplantation on the clinical outcomes in nonischemic heart failure (HF) patients under cardiac resynchronization therapy (CRT).

methodsWe studied 103 patients with nonischemic HF and sinus rhythm who underwent CRT implantation. SAECGs were obtained within 1 week before and 1 week after implantation and narrowing fQRS was defined as a decrease in fQRS from pre- to postimplantation. Echocardiography was performed before and 6 months after CRT implantation. The primary outcome was death from any cause. The secondary outcomes were hospitalization due to worsened HF and occurrence of ventricular tachyarrhythmias.

resultsOf the 103 CRT patients, 53 (51%) showed narrowing fQRS. Left ventricular end-diastolic volume and end-systolic volume were significantly reduced (both p < .001), and the left ventricular ejection fraction was significantly increased (p < .001) after CRT in patients with narrowing fQRS, but not in patients with nonnarrowing fQRS. During a median follow-up period of 33 months, patients with narrowing fQRS exhibited better survival than patients with nonnarrowing fQRS (p = .007). A lower incidence of hospitalization due to worsened HF (p < .001) and a lower occurrence of ventricular tachyarrhythmias (p = .071) were obtained in patients with narrowing fQRS. After adjusting for confounding variables, narrowing fQRS was associated with a low risk of mortality (HR 0.27, p = .006).

conclusionOur results suggested that narrowing fQRS on SAECG after CRT implantation predicts LV reverse remodeling and long-term outcomes in nonischemic HF patients.

Indexed as

Cardiac Resynchronization TherapyElectrocardiographyFemaleFollow-Up StudiesHeart FailureHumansMaleMiddle AgedRetrospective StudiesTime FactorsTreatment Outcomecardiac resynchronization therapyheart failuremortalityQRS durationsignal-averaged electrocardiogramventricular arrhythmias

Identifiers

PMID29194868
PMCPMC6931640
OpenAlexW2771710707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.