Evidence map›Paper›PMID 29194390›Full record

ReviewInternational journal of molecular sciences2017

Thyroid Disrupting Chemicals.

Valeria Calsolaro, Giuseppe Pasqualetti, Filippo Niccolai, Nadia Caraccio, Fabio Monzani

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 3 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 127 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The Impact of Shift-Work and Night Shift-Work on Thyroid: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Valeria CalsolaroDepartment of Clinical & Experimental Medicine, University of Pisa, Pisa 56125, Italy. valina82@gmail.com.
Giuseppe PasqualettiDepartment of Clinical & Experimental Medicine, University of Pisa, Pisa 56125, Italy. giuseppe.pasqualetti@gmail.com.
Filippo NiccolaiDepartment of Clinical & Experimental Medicine, University of Pisa, Pisa 56125, Italy. filippo.niccolai@alice.it.
Nadia CaraccioDepartment of Clinical & Experimental Medicine, University of Pisa, Pisa 56125, Italy. nadiacaraccio.amb@libero.it.
Fabio MonzaniDepartment of Clinical & Experimental Medicine, University of Pisa, Pisa 56125, Italy. fabio.monzani@med.unipi.it.ORCID 0000-0003-1676-098X
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocrine disruptor compounds are exogenous agents able to interfere with a gland function, exerting their action across different functional passages, from the synthesis to the metabolism and binding to receptors of the hormone produced. Several issues, such as different levels and time of exposure and different action across different ages as well as gender, make the study of endocrine disruptors still a challenge. The thyroid is very sensitive to the action of disruptors, and considering the importance of a correct thyroid function for physical and cognitive functioning, addressing this topic should be considered a priority. In this review, we examined the most recent studies, many of them concentrating on maternal and child exposure, conducted to assess the impact of industrial chemicals which showed an influence on thyroid function. So far, the number of studies conducted on that topic is not sufficient to provide solid conclusions and lead to homogeneous guidelines. The lack of uniformity is certainly due to differences in areas and populations examined, the different conditions of exposures and the remarkable inter-subject variability. Nonetheless, the European Commission for Health and Food Safety is implementing recommendations to ensure that substances identified as endocrine disruptors will be withdrawn from the market.

Indexed as

Endocrine DisruptorsEnvironmental ExposureFemaleHumansMaleMaternal ExposureThyroid GlandThyroid HormonesEndocrine DisruptorsThyroid Hormonesdisrupting compoundhypothalamus pituitary thyroid axisthyroidthyroid hormoneThyroid-Stimulating Hormone (TSH)

Identifiers

PMID29194390
PMCPMC5751186
OpenAlexW2767942941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.