Evidence map›Paper›PMID 29194387›Full record

ArticlePharmaceutics2017

Preparation and Characterization of Cabamazepine Cocrystal in Polymer Solution.

Hao Zhang, Ying Zhu, Ning Qiao, Yang Chen, Linghuan Gao

Abstract read
In one paragraph

Article in Pharmaceutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hao ZhangCollege of Materials Science and Engineering, North China University of Science and Technology, Tangshan 063210, China. zngzhang720@163.com.
Ying ZhuCollege of Materials Science and Engineering, North China University of Science and Technology, Tangshan 063210, China. YingZhu20171003@163.com.
Ning QiaoCollege of Materials Science and Engineering, North China University of Science and Technology, Tangshan 063210, China. qiaoning986@163.com.ORCID 0000-0003-3422-0821
Yang ChenCollege of Materials Science and Engineering, North China University of Science and Technology, Tangshan 063210, China. chenyang@ncst.edu.cn.
Linghuan GaoCollege of Basic Medical Sciences, North China University of Science and Technology, Tangshan 063210, China. gaolinghuan@ncst.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we attempted to prepare carbamazepine (CBZ) cocrystal through the solution method in ethanol-water solvent mixture (volume ratio 1:1) and polyvinyl pyrrolidone (PVP) solution. Nicotinamide (NIC) and saccharin (SAC) were selected as cocrystal coformers. Cocrystal screening products were characterized by Fourier Transform Infrared Spectroscopy (FTIR), Differential Scanning Calorimetry (DSC), and Powder X-ray Diffraction (PXRD) techniques. Characterization results show that in ethanol-water solvent mixture, pure CBZ-NIC cocrystal can be prepared, while CBZ-SAC cocrystal cannot be obtained. The addition of PVP can inhibit CBZ-NIC cocrystal formation and facilitate CBZ-SAC cocrystal formation.

Indexed as

carbamazepinecocrystal preparationnicotinamidepolyvinyl pyrrolidonesaccharin

Identifiers

PMID29194387
PMCPMC5750660

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.