ArticleMolecules (Basel, Switzerland)2017
In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial.
Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Triple potentiator combinations increase the functional correction of several CFTR gating mutants.npj drug discovery · 2026Article
- Mechanistic and Synergistic Evaluation of Amodiaquine-Isometamidium Combination Against Trypanosoma evansi: Integrated In Silico-In-Vitro Insights.Acta parasitologica · 2026Article
- In Vitro Screening of an In-House Library of Structurally Distinct Chemotypes Towards the Identification of Novel SARS-CoV-2 Inhibitors.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Article
- Inhibition of Acetylcholinesterase by Novel Lupinine Derivatives.Molecules (Basel, Switzerland) · 2023Article
- Quinolizidine-Based Variations and Antifungal Activity of EightMolecules (Basel, Switzerland) · 2022Article
- Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds.ACS medicinal chemistry letters · 2021Article
- A murine malaria protocol for characterizing transmission blocking benefits of antimalarial drug combinations.MalariaWorld journal · 2020Article
- Potent Antimalarial Activity of Two Arenes Linked with Triamine Designed To Have Multiple Interactions with Heme.ACS medicinal chemistry letters · 2018Article
Corrections and comments
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Authors and funding
18 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural products are a prolific source for the identification of new biologically active compounds. In the present work, we studied the in vitro and in vivo antimalarial efficacy and ADME-Tox profile of a molecular hybrid (AM1) between 4-aminoquinoline and a quinolizidine moiety derived from lupinine (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.