Evidence map›Paper›PMID 29193755›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2017

Relationship between kidney findings and systemic vascular damage in elderly hypertensive patients without overt cardiovascular disease.

Giulio Geraci, Giuseppe Mulè, Gabriella Paladino, Marta Maria Zammuto, Antonella Castiglia, Emilia Scaduto, Federica Zotta, Calogero Geraci, Antonio Granata, Pasquale Mansueto and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Relationship Between 8-iso-prostaglandin-FLife (Basel, Switzerland) · 2025
    Article
  5. Review
  6. Evaluation of Intra-Renal Stiffness in Patients with Primary Aldosteronism.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022
    Article
  7. Observational
  8. Renal resistive index: Beyond the hemodynamics.Journal of clinical hypertension (Greenwich, Conn.) · 2020
    Article
  9. Choroidal thickness is associated with renal hemodynamics in essential hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2020
    Article
  10. The prognostic role of the cardio-ankle vascular index.Journal of clinical hypertension (Greenwich, Conn.) · 2019
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Giulio GeraciDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), Unit of Nephrology and Hypertension, European Society of Hypertension Excellence Center, University of Palermo, Palermo, Italy.ORCID http://orcid.org/0000-0003-3806-1151
Giuseppe MulèDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), Unit of Nephrology and Hypertension, European Society of Hypertension Excellence Center, University of Palermo, Palermo, Italy.ORCID http://orcid.org/0000-0002-8500-8671
Gabriella PaladinoDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), Unit of Geriatrics, University of Palermo, Palermo, Italy.
Marta Maria ZammutoDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), Unit of Nephrology and Hypertension, European Society of Hypertension Excellence Center, University of Palermo, Palermo, Italy.
Antonella CastigliaDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), Unit of Nephrology and Hypertension, European Society of Hypertension Excellence Center, University of Palermo, Palermo, Italy.
Emilia ScadutoDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), Unit of Nephrology and Hypertension, European Society of Hypertension Excellence Center, University of Palermo, Palermo, Italy.
Federica ZottaDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), Unit of Nephrology and Hypertension, European Society of Hypertension Excellence Center, University of Palermo, Palermo, Italy.
Calogero GeraciDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), Unit of Nephrology and Hypertension, European Society of Hypertension Excellence Center, University of Palermo, Palermo, Italy.
Antonio Granata"San Giovanni di Dio" Hospital, Unit of Nephrology and Dialysis, Agrigento, Italy.
Pasquale MansuetoDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), Unit of Geriatrics, University of Palermo, Palermo, Italy.
Santina CottoneDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), Unit of Nephrology and Hypertension, European Society of Hypertension Excellence Center, University of Palermo, Palermo, Italy.
European Society of Hypertension · ITUniversity of Palermo · ITNuovo Ospedale San Giovanni di Dio · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few studies have investigated the influence of age on the relationships between systemic vascular damage, kidney dysfunction, and intrarenal hemodynamic changes in patients with hypertension without overt cardiovascular disease. The authors enrolled 126 elderly patients with hypertension (aged ≥65 years) and 350 nonelderly patients with hypertension (aged <65 years). Carotid intima-media thickness, renal resistive index, and aortic pulse wave velocity were performed in all patients. Elderly patients with hypertension had lower estimated glomerular filtration rates and higher albuminuria, renal resistive index, carotid intima-media thickness, and aortic pulse wave velocity compared with nonelderly patients with hypertension (P < .001). Carotid intima-media thickness independently correlated with renal resistive index and estimated glomerular filtration rate in nonelderly patients with hypertension, whereas it was significantly related to renal resistive index only in elderly patients with hypertension. Aortic pulse wave velocity was independently associated with albuminuria in nonelderly patients with hypertension, whereas it did not independently correlate with any indexes of renal damage in elderly patients with hypertension. Age is an important modifier of the relationships between renal function and renal hemodynamics with subclinical vascular involvement in elderly persons without cardiovascular disease.

Indexed as

Carotid ArteriesHypertensionAgedBlood Flow VelocityBlood PressureCarotid Intima-Media ThicknessCross-Sectional StudiesFemaleGlomerular Filtration RateHemodynamicsHumansItalyKidneyMaleStatistics as TopicUltrasonography, Doppler, ColorElderlyHypertensionRenal diseaseRenal haemodyanmicsSystemic vascular damageVascular disease

Identifiers

PMID29193755
PMCPMC8030830
OpenAlexW2768878627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.