ArticleNeurogastroenterology and motility2018
Jackhammer esophagus: Assessing the balance between prepeak and postpeak contractile integral.
Article in Neurogastroenterology and motility, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Reduced esophagogastric junction contractile integral in patients with ineffective esophageal motility.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Compartmentalized pressurization is a novel prognostic factor for hypercontractile esophagus.Neurogastroenterology and motility · 2024Article
- High-Pressure Tactics: Jackhammer Esophagus-Diagnosing Is Easier than Treating.Digestive diseases and sciences · 2022Article
- Symptom Severity Related With Contraction Peaks in Patients With Jackhammer Esophagus.Journal of neurogastroenterology and motility · 2021Article
- [Diagnosis of Dysphagia: High Resolution Manometry & EndoFLIP].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2021Review
- Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0Neurogastroenterology and motility · 2021Review
- The hypercontractile esophagus: Still a tough nut to crack.Neurogastroenterology and motility · 2020Review
- Chaotic peak propagation in patients with Jackhammer esophagus.Neurogastroenterology and motility · 2020Article
- Clinical outcomes and safety of high-resolution manometry guided superficial partial circular muscle myotomy in per-oral endoscopic myotomy for Jackhammer esophagus: Two cases report.World journal of clinical cases · 2019Article
- The Relevance of Spastic Esophageal Disorders as a Diagnostic Category.Current gastroenterology reports · 2018Review
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Authors and funding
5 authors.
Funding
Abstract
backgroundWe hypothesized that symptoms in Jackhammer esophagus (JH) are associated with an imbalance between the prepeak and postpeak phases of contraction. Thus, we developed a method to distinguish the contractile integral components of prepeak and postpeak phase contractile activity to determine the contribution of each phase and their association with dysphagia.
methodsPatients diagnosed with JH were enrolled and compared to controls. The first five intact swallows during manometry were analyzed. A single swallow was divided into a prepeak and postpeak phase. The contractile integral of each phase and its corresponding time-controlled integral were computed. All metrics were compared between controls and JH patients subcategorized by the impaction dysphagia question (IDQ) score with cut-off of 6. KEY
resultsThirty eight JH patients and 71 controls were included. Twelve JH patients had IDQ ≤ 6 and 26 with IDQ > 6. JH patients had higher contractile integral in both phases, and a higher ratio between postpeak to prepeak contractile integral independent of duration. Similarly, JH patients with an IDQ > 6 had higher contractile metrics than those with IDQ ≤ 6. There was a correlation between the IDQ score and the ratio within the postpeak to prepeak contractile integral (r = .375).
conclusionsAbnormalities in contractile integral of the postpeak phase are more significant in JH with higher dysphagia scores Although the total postpeak contractile integral was higher in symptomatic patients, this was associated with longer duration of postpeak activity suggesting that dysphagia patients with JH have a defect in the postpeak phase of peristalsis.
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