Evidence map›Paper›PMID 29193335›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2018

C9orf72 repeat expansions as genetic modifiers for depression in spinocerebellar ataxias.

Karla P Figueroa, Shi-Rui Gan, Susan Perlman, George Wilmot, Christopher M Gomez, Jeremy Schmahmann, Henry Paulson, Vikram G Shakkottai, Sarah H Ying, Theresa Zesiewicz and 7 more

Open access · bronzeAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 14 institutions in 2 countries.

Karla P FigueroaDepartment of Neurology, University of Utah, Salt Lake City, Utah, USA.
Shi-Rui GanDepartment of Neurology and Institute of Neurology, First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Susan PerlmanDepartment of Neurology, University of California Los Angeles, Los Angeles, California, USA.
George WilmotDepartment of Neurology, Emory University, Atlanta, Georgia, USA.
Christopher M GomezDepartment of Neurology, University of Chicago, Chicago, Illinois, USA.
Jeremy SchmahmannDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Henry PaulsonDepartment of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Vikram G ShakkottaiDepartment of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Sarah H YingDepartment of Neurology, Johns Hopkins University, Baltimore, Maryland, USA.
Theresa ZesiewiczDepartment of Neurology, University of South Florida, Tampa, Florida, USA.
Khalaf BusharaDepartment of Neurology, University of Minnesota, Minneapolis, Minnesota, USA.
Michael GeschwindDepartment of Neurology, University of California San Francisco, San Francisco, California, USA.
Guangbin XiaDepartment of Neurology, University of New Mexico, Albuquerque, USA.
S H SubramonyDepartment of Neurology, University of New Mexico, Albuquerque, USA.
Tetsuo AshizawaHouston Methodist Research Institute, Houston, Texas, USA.
Stefan M PulstDepartment of Neurology, University of Utah, Salt Lake City, Utah, USA.
Sheng-Han KuoDepartment of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
University of Michigan–Ann Arbor · USUniversity of New Mexico · USUniversity of Utah · USColumbia University · USEmory University · USFujian Medical University · CNHarvard University · USHouston Methodist · USJohns Hopkins University · USUniversity of California, Los Angeles · USUniversity of California, San Francisco · USUniversity of Chicago · USUniversity of Minnesota · USUniversity of South Florida · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Spinocerebellar Ataxia Type 2 Gene and Gene ProductR37NS033123 · NINDS · UNIVERSITY OF UTAH · PI PULST, STEFAN M. · 2014 to 2020
$3.6M
SPINOCEREBELLAR ATAXIA TYPE 2--GENE AND GENE PRODUCTR01NS033123 · NINDS · UNIVERSITY OF UTAH · PI PULST, STEFAN M. · 1996 to 2012
$2.9M
Clinical Research Consortium for Spinocerebellar AtaxiasRC1NS068897 · NINDS · UNIVERSITY OF FLORIDA · PI ASHIZAWA, TETSUO · 2009 to 2010
$1.0M
The role of glucocerebrosidase and chaperone_mediated autophagy in Parkinsons disK08NS083738 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KUO, SHENG-HAN · 2013 to 2017
$940k
Drug Discovery for Spinocerebellar Ataxia Type 2 (SCA2)RC4NS073009 · NINDS · UNIVERSITY OF UTAH · PI PULST, STEFAN M., SCOLES, DANIEL R · 2010 to 2010
$835k
NIEHS NIH HHS P30 ES009089NINDS NIH HHS K08 NS083738NINDS NIH HHS R01 NS033123NINDS NIH HHS R37 NS033123NINDS NIH HHS RC1 NS068897NINDS NIH HHS RC4 NS073009
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAge of OnsetC9orf72 ProteinDepressionDNA Repeat ExpansionFemaleHumansMaleMiddle AgedSpinocerebellar AtaxiasSurveys and QuestionnairesC9orf72 ProteinC9orf72 protein, human

Identifiers

PMID29193335
PMCPMC6200142
OpenAlexW2769573785

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.