SynthesisSuicide & life-threatening behavior2019
Metaanalysis of Mood and Substance Use Disorders in Proximal Risk for Suicide Deaths.
Synthesis in Suicide & life-threatening behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- Risk factors for suicide in adults: systematic review and meta-analysis of psychological autopsy studies.Evidence-based mental health · 2022Pooled it
- Suicides in Mood Disorders in Psychiatric Settings in Nordic National Register-Based Studies.Frontiers in psychiatry · 2020Pooled it
- A secondary analysis of a brief video intervention on suicidal ideation among recent rape victims.Psychological services · 2021Trial
- Pilot RCT of the Attempted Suicide Short Intervention Program (ASSIP) adapted for rapid delivery during hospitalization to adult suicide attempt patients with substance use problems.General hospital psychiatryTrial
- Self-stigma and suicide cognitions in substance use disorder: the mediating role of psychological distress and the moderating role of social support.BMC psychiatry · 2026Article
- Applying the reinforcer pathology model to alcohol use and suicide risk: An initial test.Journal of the experimental analysis of behavior · 2026Article
- Suicide risks associated with cardiovascular disease in persons with alcohol use disorder.Annals of epidemiology · 2026Article
- Relationship Between Substance Use and Suicide Behavior During the COVID-19 Pandemic: A Systematic Review and Random-Effects Proportions Meta-Analysis.Journal of clinical medicine · 2026Review
- Childhood exposure to interpersonal and animal-directed violence: adversity profiles and adult suicidality.Frontiers in psychiatry · 2026Article
- Development and External Validation of a Prediction Model to Identify Suicide Attempters in Treatment-Naive Adolescents With Major Depressive Disorder.Depression and anxiety · 2026Article
- Evaluation of suicide patterns, causes and triggering factors in children and adolescents.BMC pediatrics · 2025Article
- The relationship between suicidal ideation and eating disorders in the context of violence experiences.BMC psychiatry · 2025Article
- Association of substance use with suicide mortality: An updated systematic review and meta-analysis.Drug and alcohol dependence reports · 2025Review
- Article
- A cultural script for suicide among White men in the Mountain West Region of the United States.The American psychologist · 2025Review
- Neighborhood predictors of suicide and firearm suicide in Detroit, Michigan.Injury epidemiology · 2024Article
- Stress and alcohol-related coping mechanisms linking lifetime suicide ideation and attempt to multidimensional quality of life.Journal of affective disorders · 2024Article
- Association of medical conditions and firearm suicide among legal handgun purchasers in California: a case-control study.Injury epidemiology · 2023Article
- Shared genetic and environmental etiology between substance use disorders and suicidal behavior.Psychological medicine · 2023Article
- Postpartum Opioid-Related Mortality in Patients With Public Insurance.Obstetrics and gynecology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
Evidence for proximal risk factors for suicide is based on case-control psychological autopsy studies, with these reports showing that mood and substance use disorders are the most prevalent mental disorders among suicide decedents worldwide and are associated with marked risk. However, moderators of risk and the degree of risk associated with (nonalcohol) drug use disorder are unknown. A comprehensive search was used to identify 35 case-control psychological autopsy studies published worldwide over a 30-year period that were metaanalyzed using random effects models. Major depression, odds ratio (95% confidence interval) = 9.14 (5.53, 15.09), and drug use disorder, OR (95% CI) = 7.18 (3.22, 16.01), had large effect sizes, among other results. Risk estimates associated with major depression were greater in studies with a larger proportion of women and those conducted in Asia compared with other regions. There was no evidence of publication bias or that any one study had a disproportionate impact on findings. Risk for suicide associated with major depression appears to be moderated by sex and/or world region. Drug use disorder is a potent risk factor, illustrating the importance of assessing drug use in clinical risk assessment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.