Evidence map›Paper›PMID 29193176›Full record

ReviewThe Journal of physiology2018

Using voltage-sensor toxins and their molecular targets to investigate Na

John Gilchrist, Frank Bosmans

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Suzetrigine, a NaMolecules (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Article
  5. Structural basis for high-voltage activation and subtype-specific inhibition of human NaProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Carboxamides as Modulators of Sodium Channels.ACS medicinal chemistry letters · 2020
    Article
  11. 2-Amino-N-heteroaryl-nicotimamides as NaACS medicinal chemistry letters · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

John GilchristDepartment of Physiology, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Frank BosmansDepartment of Physiology, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.ORCID 0000-0002-6476-235X
Johns Hopkins University · US

Funding

Voltage-gated sodium channel modulation by Beta1 and Beta4 (R01NS091352)R01NS091352 · NINDS · JOHNS HOPKINS UNIVERSITY · PI BOSMANS, FRANK GERT WERNER · 2015 to 2019
$1.3M
The role of auxiliary subunits in the sodium channel signaling complexF31NS084646 · NINDS · JOHNS HOPKINS UNIVERSITY · PI GILCHRIST, JOHN MICHAEL · 2014 to 2016
$129k
NINDS NIH HHS F31 NS084646NINDS NIH HHS R01 NS091352
6 · The paper itself

Abstract

Voltage-gated sodium (Na

Indexed as

AnimalsHumansIon Channel GatingMembrane PotentialsNAV1.8 Voltage-Gated Sodium ChannelToxins, BiologicalVoltage-Gated Sodium Channel BlockersNAV1.8 Voltage-Gated Sodium ChannelToxins, BiologicalVoltage-Gated Sodium Channel BlockersgatingNaV1.8S3b-S4 motifscorpion toxinspider toxinvoltage-sensing domain

Identifiers

PMID29193176
PMCPMC5978285
OpenAlexW2770462389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.