ArticleEye (London, England)2018
EDTA chelation for symptomatic band keratopathy: results and recurrence.
Article in Eye (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 44 citations in OpenAlex.
- Band keratopathy and conjunctival calcification in end-stage kidney disease: epidemiology, pathophysiology and clinical management.Clinical kidney journal · 2026Review
- Effects of ethylenediaminetetraacetic acid chelation for calcific band keratopathy on corneal topography assessed by fourier harmonic analysis.Japanese journal of ophthalmology · 2025Article
- Phototherapeutic keratectomy for calcific band keratopathy secondary to multiple myeloma.Journal of surgical case reports · 2025Article
- CD46 Is a Protein Receptor for Human Adenovirus Type 64.Viruses · 2024Article
- Modified Transepithelial Phototherapeutic Keratectomy for Band Keratopathy.Journal of clinical medicine · 2024Article
- Article
- On-spot preparation of EDTA solution for the treatment of band keratopathy: a case report.International journal of ophthalmology · 2024Article
- Article
- Bacteriostatic and Antibiofilm Efficacy of a Nisin Z Solution against Co-Cultures ofLife (Basel, Switzerland) · 2023Article
- Ocular safety of intravitreal ethylene diamine tetra acetic acid (EDTA): An experimental feasibility study.Toxicology reports · 2023Article
- Subepithelial white deposition in the cornea associated with silicone oil and surgical management: a case report.Frontiers in medicine · 2023Article
- Clinical profile and demographic distribution of band shaped keratopathy in India: A study of 8801 patients.Indian journal of ophthalmology · 2022Article
- Hyperopia-Correcting Phototherapeutic Keratectomy and Its Comparison With Conventional Phototherapeutic Keratectomy.Frontiers in medicine · 2022Article
- Superficial Keratectomy: A Review of Literature.Frontiers in medicine · 2022Review
- Clinical outcomes of simultaneous phototherapeutic keratectomy and photoastigmatic keratectomy.Scientific reports · 2021Article
- Removal of calcific band keratopathy without ethylenediaminetetraacetic acid (EDTA) in eyes with limited visual potential.Clinical ophthalmology (Auckland, N.Z.) · 2018Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PurposeTo identify causes of symptomatic band keratopathy, and assess the results and long-term recurrence rates following chelation with topical ethylene-diamine-tetra-acetic acid (EDTA).Patients and methodsA retrospective review of surgical logbooks identified patients managed by EDTA chelation for symptomatic band keratopathy from 2009 to 2015.ResultsWe identified 108 cases; 89 case notes were available for analysis. Most cases of band keratopathy were idiopathic (36%). The most commonly identified underlying diagnosis was long-term topical glaucoma therapy (27%). Median presenting visual acuity was 6/18 (range 6/6-NPL) with the visual axis affected in 97.8% of cases. Treatment involved corneal epithelium removal, recurrent application of topical EDTA, and subsequent debridement. The mean duration of the operation was 20 min (range 10-45). Mean initial follow-up time was 40 days, and the visual axis was clear in 97.8%. Visual acuity was maintained or improved in 79.8%, with 13.5% improving by two lines or more. The mean length of follow-up was 581 days (median 374, maximum 2438). Twenty-five eyes (28.1%) showed localised recurrence of calcium with a mean time of 546 days (median 374), but only four cases required repeat EDTA chelation. The median time between operations was 430 days. Thirty-two per cent of the recurrence cases were associated with hypotony or chronic presence of silicone oil.ConclusionsChelation of calcium with topical EDTA is a safe and effective treatment for band keratopathy. Visual acuity improves in most eyes and while the rate of recurrence is moderate, the need for retreatment is low (4.5% overall).
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