Evidence map›Paper›PMID 29192382›Full record

ArticleMedical & biological engineering & computing2018

Multimodal molecular 3D imaging for the tumoral volumetric distribution assessment of folate-based biosensors.

Gerardo J Ramírez-Nava, Clara L Santos-Cuevas, Isaac Chairez, Liliana Aranda-Lara

Abstract read
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In one paragraph

Article in Medical & biological engineering & computing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Gerardo J Ramírez-NavaInstituto Nacional de Investigaciones Nucleares (ININ), 52750, Ocoyoacac, Estado de México, Mexico.
Clara L Santos-CuevasInstituto Nacional de Investigaciones Nucleares (ININ), 52750, Ocoyoacac, Estado de México, Mexico. clara_letici@yahoo.com.mx.
Isaac ChairezUnidad Profesional Interdisciplinaria de Biotecnología (UPIBI), Instituto Politécnico Nacional (IPN), Gustavo A. Madero, 07340, Mexico City, Mexico.
Liliana Aranda-LaraInstituto Nacional de Investigaciones Nucleares (ININ), 52750, Ocoyoacac, Estado de México, Mexico.
Instituto Nacional de Investigaciones Nucleares · MXInstituto Politécnico Nacional · MXUniversidad Autónoma del Estado de México · MX

Funding

Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX) IPN-SIPCOFAA-2015-0344Consejo Nacional de Ciencia y Tecnología CONACYT-SEP-CB-2014-01-242443-CONACyTPDCPN-2015-01-1040
6 · The paper itself

Abstract

The aim of this study was to characterize the in vivo volumetric distribution of three folate-based biosensors by different imaging modalities (X-ray, fluorescence, Cerenkov luminescence, and radioisotopic imaging) through the development of a tridimensional image reconstruction algorithm. The preclinical and multimodal Xtreme imaging system, with a Multimodal Animal Rotation System (MARS), was used to acquire bidimensional images, which were processed to obtain the tridimensional reconstruction. Images of mice at different times (biosensor distribution) were simultaneously obtained from the four imaging modalities. The filtered back projection and inverse Radon transformation were used as main image-processing techniques. The algorithm developed in Matlab was able to calculate the volumetric profiles of

Indexed as

Imaging, Three-DimensionalMolecular ImagingTumor BurdenAdministration, IntravenousAlgorithmsAnimalsBiosensing TechniquesCalibrationFolic AcidMice, NudeNeoplasmsTissue DistributionFolic AcidFolate-based biosensorsInverse Radon transformationIn vivo imagingTridimensional reconstruction

Identifiers

PMID29192382
OpenAlexW2772983876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.