Evidence map›Paper›PMID 29192365›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

EANM/EARL FDG-PET/CT accreditation - summary results from the first 200 accredited imaging systems.

Andres Kaalep, Terez Sera, Wim Oyen, Bernd J Krause, Arturo Chiti, Yan Liu, Ronald Boellaard

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 2 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 2 syntheses or guidelines pooled it, 164 citations in OpenAlex.

  1. EANM practice guideline for quantitative SPECT-CT.European journal of nuclear medicine and molecular imaging · 2023
    Guideline
  2. Pooled it
  3. Trial
  4. Diagnostic accuracy ofEuropean journal of nuclear medicine and molecular imaging · 2026
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  5. Applications of artificial intelligence in nuclear medicine.Zeitschrift fur medizinische Physik · 2026
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  6. Real-world application ofEuropean journal of nuclear medicine and molecular imaging · 2026
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  9. Real world experience with [Frontiers in endocrinology · 2026
    Article
  10. Article
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  12. Standardization of PET/CT Performance Requirements for Whole-Body Quantitative Imaging: An International Proposal.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Review
  13. Article
  14. Review
  15. Radiomics with Clinical Data and [Diagnostics (Basel, Switzerland) · 2025
    Article
  16. Article
  17. Color Maps: Facilitating the Clinical Impact of Quantitative MRI.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  18. Article
  19. Article
  20. Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 7 countries.

Andres KaalepDepartment of Medical Technology, North Estonia Medical Centre Foundation, J. Sutiste Str 19, 13419, Tallinn, Estonia. kaalep@gmail.com.ORCID 0000-0002-5593-8886
Terez SeraDepartment of Nuclear Medicine, University of Szeged, Szeged, Hungary.
Wim OyenThe Institute of Cancer Research, Division of Radiotherapy and Imaging, Department of Nuclear Medicine, The Royal Marsden Hospital, London, UK.
Bernd J KrauseDepartment of Nuclear Medicine, Rostock University Medical Center, Rostock, Germany.
Arturo ChitiDepartment of Nuclear Medicine, Humanitas Clinical and Research Center, Rozzano, MI, Italy.
Yan LiuEuropean Organisation for Research and Treatment of Cancer (EORTC) Headquarters, Brussels, Belgium.
Ronald BoellaardOn behalf of EANM Research Limited (EARL), Vienna, Austria.
European Organisation for Research and Treatment of Cancer · BEHumanitas University · ITInstitute of Cancer Research · GBNorth Estonia Medical Centre · EEUniversity Medical Center Groningen · NLUniversity of Rostock · DEUniversity of Szeged · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFrom 2010 until July 2016, the EANM Research Ltd. (EARL) FDG-PET/CT accreditation program has collected over 2500 phantom datasets from approximately 200 systems and 150 imaging sites worldwide. The objective of this study is to report the findings and impact of the accreditation program on the participating PET/CT systems.

methodsTo obtain and maintain EARL accredited status, sites were required to complete and submit two phantom scans - calibration quality control (CalQC), using a uniform cylindrical phantom and image quality control (IQQC), using a NEMA NU2-2007 body phantom. Average volumetric SUV bias and SUV recovery coefficients (RC) were calculated and the data evaluated on the basis of quality control (QC) type, approval status, PET/CT system manufacturer and submission order.

resultsSUV bias in 5% (n = 96) of all CalQC submissions (n = 1816) exceeded 10%. After corrective actions following EARL feedback, sites achieved 100% compliance within EARL specifications. 30% (n = 1381) of SUVmean and 23% (n = 1095) of SUVmax sphere recoveries from IQQC submissions failed to meet EARL accreditation criteria while after accreditation, failure rate decreased to 12% (n = 360) and 9% (n = 254), respectively. Most systems demonstrated longitudinal SUV bias reproducibility within ±5%, while RC values remained stable and generally within ±10% for the four largest and ±20% for the two smallest spheres.

conclusionsRegardless of manufacturer or model, all investigated systems are able to comply with the EARL specifications. Within the EARL accreditation program, gross PET/CT calibration errors are successfully identified and longitudinal variability in PET/CT performances reduced. The program demonstrates that a harmonising accreditation procedure is feasible and achievable.

Indexed as

Fluorodeoxyglucose F18Nuclear MedicineSocieties, MedicalAccreditationCalibrationPhantoms, ImagingPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18EARL accreditationHarmonisationPerformancePET/CTQuantification

Identifiers

PMID29192365
PMCPMC5787222
OpenAlexW2773306697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.