Evidence map›Paper›PMID 29192360›Full record

ReviewHeart failure reviews2018

Hyperglycemia-induced cardiac contractile dysfunction in the diabetic heart.

Raphael M Singh, Tahreem Waqar, Frank C Howarth, Ernest Adeghate, Keshore Bidasee, Jaipaul Singh

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Heart failure reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04534894 (Single-center Clinical Study of Early Diagnosis of Diabetic Cardiomyopathy With Fluorescence Lifetime Imaging Microscopy), which is not on this map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04534894 unknown statusnot on this mapstarted 2020, after this paper: background citation

Single-center Clinical Study of Early Diagnosis of Diabetic Cardiomyopathy With Fluorescence Lifetime Imaging Microscopy (FLIM)

TypeobservationalSponsorXinhua Hospital, Shanghai Jiao Tong University School of MedicineRan2020 to 2022Enrolled243ConditionsDiabetic CardiomyopathiesArmsfluorescence lifetime imaging microscopy
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Review
  9. [Quercetin ameliorates myocardial injury in diabetic rats by regulating L-type calcium channels].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Exploring the Biological Effects of Anti-Diabetic Vanadium Compounds in the Liver, Heart and Brain.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Adropin's Role in Energy Homeostasis and Metabolic Disorders.International journal of molecular sciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Raphael M SinghSchool of Forensic and Applied Sciences, University of Central Lancashire, Preston, England, PR1 2HE, UK. raphael_singh@yahoo.com.
Tahreem WaqarSchool of Forensic and Applied Sciences, University of Central Lancashire, Preston, England, PR1 2HE, UK.
Frank C HowarthDepartment of Physiology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Ernest AdeghateDepartment of Human Anatomy, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Keshore BidaseeDepartment of Pharmacology and Experimental Neurosciences, University of Nebraska Medical Centre, Omaha, NE, 68198, USA.
Jaipaul SinghSchool of Forensic and Applied Sciences, University of Central Lancashire, Preston, England, PR1 2HE, UK.
University of Central Lancashire · GBUnited Arab Emirates University · AEUniversity of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of a diabetic cardiomyopathy is a multifactorial process, and evidence is accumulating that defects in intracellular free calcium concentration [Ca

Indexed as

Diabetic CardiomyopathiesHumansHyperglycemiaMyocardial ContractionMyocardiumSarcoplasmic ReticulumSarcoplasmic Reticulum Calcium-Transporting ATPasesSodium-Calcium ExchangerSarcoplasmic Reticulum Calcium-Transporting ATPasesSodium-Calcium ExchangerCalcium transients [Ca2+]iContractile dysfunctionDiabetic cardiomyopathyHyperglycemiaSarcoplasmic reticulum calcium ATPase (SERCA)

Identifiers

PMID29192360
OpenAlexW2772333344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.