Evidence map›Paper›PMID 29192338›Full record

ArticleChromosoma2018

Evolutionary trends in animal ribosomal DNA loci: introduction to a new online database.

Jana Sochorová, Sònia Garcia, Francisco Gálvez, Radka Symonová, Aleš Kovařík

Open access · hybridAbstract read
In one paragraph

Article in Chromosoma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
21.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 143 citations in OpenAlex.

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  9. Assessing Human Ribosomal DNA Variation and Its Association With Phenotypic Outcomes.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
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  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jana SochorováInstitute of Biophysics, Academy of Sciences of the Czech Republic, CZ-61265, Brno, Czech Republic.
Sònia GarciaInstitut Botànic de Barcelona (IBB-CSIC-ICUB), Passeig del Migdia s/n, 08038, Barcelona, Catalonia, Spain.
Francisco GálvezBioscripts-Centro de Investigación y Desarrollo de Recursos Científicos, 41012, Sevilla, Andalusia, Spain.
Radka SymonováFaculty of Science, University of Hradec Kralove, Hradecka 1285, CZ-50003, Hradec Kralove, Czech Republic.
Aleš KovaříkInstitute of Biophysics, Academy of Sciences of the Czech Republic, CZ-61265, Brno, Czech Republic. kovarik@ibp.cz.ORCID 0000-0003-2896-0698
Czech Academy of Sciences · CZCentro de Investigación y Desarrollo · ESInstitut Botànic de Barcelona · ESUniversity of Hradec Králové · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ribosomal DNA (rDNA) loci encoding 5S and 45S (18S-5.8S-28S) rRNAs are important components of eukaryotic chromosomes. Here, we set up the animal rDNA database containing cytogenetic information about these loci in 1343 animal species (264 families) collected from 542 publications. The data are based on in situ hybridisation studies (both radioactive and fluorescent) carried out in major groups of vertebrates (fish, reptiles, amphibians, birds, and mammals) and invertebrates (mostly insects and mollusks). The database is accessible online at www.animalrdnadatabase.com . The median number of 45S and 5S sites was close to two per diploid chromosome set for both rDNAs despite large variation (1-74 for 5S and 1-54 for 45S sites). No significant correlation between the number of 5S and 45S rDNA loci was observed, suggesting that their distribution and amplification across the chromosomes follow independent evolutionary trajectories. Each group, irrespective of taxonomic classification, contained rDNA sites at any chromosome location. However, the distal and pericentromeric positions were the most prevalent (> 75% karyotypes) for 45S loci, while the position of 5S loci was more variable. We also examined potential relationships between molecular attributes of rDNA (homogenisation and expression) and cytogenetic parameters such as rDNA positions, chromosome number, and morphology.

Indexed as

Evolution, MolecularQuantitative Trait LociAnimalsChromosomesDatabases, GeneticDNA, RibosomalInternetKaryotypeWeb BrowserDNA, Ribosomal45S rDNA5S rDNAAnimalCytogeneticsDatabaseRibosomal RNA

Identifiers

PMID29192338
PMCPMC5818627
OpenAlexW2775405796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.