ArticleScientific reports2017
Low resistance to chytridiomycosis in direct-developing amphibians.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 68 citations in OpenAlex.
- Overcoming Detection Lag in a Cryptic Panzootic: Chytrid Invasion Linked to Historically Enigmatic Amphibian Declines in the Brazilian Atlantic Forest.Molecular ecology · 2026Article
- Differential skin-bacteriome-mediated defense against chytridiomycosis in two neotropical frog species.Animal microbiome · 2026Article
- Connecting habitats, boosting disease resistance: Spatial connectivity enhances amphibian microbiome defenses against fungal pathogen.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Localized transmission of an aquatic pathogen drives hidden epidemics and population collapse in a terrestrial host.Nature ecology & evolution · 2026Article
- Coinfection with chytrid genotypes drives divergent infection dynamics reflecting regional distribution patterns.Communications biology · 2023Article
- Selection of an anti-pathogen skin microbiome following prophylaxis treatment in an amphibian model system.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Low microbiome diversity in threatened amphibians from two biodiversity hotspots.Animal microbiome · 2022Article
- Signatures of functional bacteriome structure in a tropical direct-developing amphibian species.Animal microbiome · 2022Article
- Article
- Differences in Fungal Disease Dynamics in Co-occurring Terrestrial and Aquatic Amphibians.EcoHealth · 2020Article
- Assessing amphibian disease risk across tropical streams while accounting for imperfect pathogen detection.Oecologia · 2020Article
- Bullfrog farms release virulent zoospores of the frog-killing fungus into the natural environment.Scientific reports · 2019Article
- Low-load pathogen spillover predicts shifts in skin microbiome and survival of a terrestrial-breeding amphibian.Proceedings. Biological sciences · 2019Article
- Arthropod-bacteria interactions influence assembly of aquatic host microbiome and pathogen defense.Proceedings. Biological sciences · 2019Article
- Skin-associated lactic acid bacteria from North American bullfrogs as potential control agents of Batrachochytrium dendrobatidis.PloS one · 2019Article
- Hybrids of amphibian chytrid show high virulence in native hosts.Scientific reports · 2018Article
- Frog Skin Innate Immune Defences: Sensing and Surviving Pathogens.Frontiers in immunology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Host-generalist pathogens sporadically infect naive hosts, potentially triggering epizootics. The waterborne fungus Batrachochytrium dendrobatidis (Bd) is linked to declines of hundreds of amphibian species with aquatic larvae. Although several population declines and extinctions attributed to Bd have been reported among cryptic species undergoing direct development away from water, epidemiological studies focused on these terrestrial frogs are lacking. Our field data support that terrestrial direct-developing hosts are less exposed to Bd during their ontogeny than species with aquatic larvae, and thus they might lack adaptive responses against waterborne chytrids. Using controlled laboratory experiments, we exposed wild-caught amphibian species with terrestrial and aquatic life histories to Bd and found that direct developers showed more rapid increases in infection loads and experienced higher mortality rates than species with aquatic larvae. Our findings provide novel information about host responses to generalist pathogens and specifically show that our focal direct developing species have low resistance to Bd infections. Finally, our results underscore that we should not ignore Bd as a potential threat to direct developing species simply because they are less exposed to Bd in nature; instead future amphibian conservation plans should include efforts to safeguard hundreds of direct-developing amphibian species globally.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.