Evidence map›Paper›PMID 29192208›Full record

ArticleScientific reports2017

Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo.

Cheng Xue Qin, Siobhan B Finlayson, Annas Al-Sharea, Mitchel Tate, Miles J De Blasio, Minh Deo, Sarah Rosli, Darnel Prakoso, Colleen J Thomas, Helen Kiriazis and 8 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Guidelines for in vivo mouse models of myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2021
    Guideline
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Annexin Animal Models-From Fundamental Principles to Translational Research.International journal of molecular sciences · 2021
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Therapeutic Potential of Lipoxin AACS pharmacology & translational science · 2020
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Cheng Xue QinBaker Heart & Diabetes Institute, Melbourne, 3004, Australia. chengxuehelena.qin@baker.edu.au.
Siobhan B FinlaysonBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Annas Al-ShareaBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Mitchel TateBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Miles J De BlasioBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Minh DeoBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Sarah RosliBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.ORCID 0000-0001-7820-1484
Darnel PrakosoBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Colleen J ThomasDept of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, 3086, Australia.
Helen KiriazisBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Eleanor GouldBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Yuan H YangCentre for Inflammatory Diseases, Monash University, Clayton, 3168, VIC, Australia.
Eric F MorandCentre for Inflammatory Diseases, Monash University, Clayton, 3168, VIC, Australia.ORCID 0000-0002-9507-3338
Mauro PerrettiWilliam Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom.ORCID 0000-0003-2068-3331
Andrew J MurphyBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Xiao-Jun DuBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Xiao-Ming GaoBaker Heart & Diabetes Institute, Melbourne, 3004, Australia.
Rebecca H RitchieBaker Heart & Diabetes Institute, Melbourne, 3004, Australia. rebecca.ritchie@baker.edu.au.
Baker Heart and Diabetes Institute · AUMonash University · AULa Trobe University · AUQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endogenous anti-inflammatory annexin-A1 (ANX-A1) plays an important role in preserving left ventricular (LV) viability and function after ischaemic insults in vitro, but its long-term cardioprotective actions in vivo are largely unknown. We tested the hypothesis that ANX-A1-deficiency exaggerates inflammation, haematopoietic stem progenitor cell (HSPC) activity and LV remodelling in response to myocardial ischaemia in vivo. Adult ANX - A1

Indexed as

Hematopoietic Stem Cell MobilizationAnimalsAnnexin A1Disease Models, AnimalHematopoietic Stem CellsMacrophagesMaleMiceMice, KnockoutMyocardial InfarctionMyocardial IschemiaMyocarditisNecrosisRatsAnnexin A1

Identifiers

PMID29192208
PMCPMC5709412
OpenAlexW2769705721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.