ArticleNature communications2017
Directed self-assembly of fluorescence responsive nanoparticles and their use for real-time surface and cellular imaging.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Self-assembled and intestine-targeting florfenicol nano-micelles effectively inhibit drug-resistantJournal of pharmaceutical analysis · 2025Article
- Tracking tumor heterogeneity and progression with near-infrared II fluorophores.Exploration (Beijing, China) · 2023Review
- Transcellular Transport Behavior of the Intact Polymeric Mixed Micelles with Different Polymeric Ratios.AAPS PharmSciTech · 2023Article
- Exploiting directed self-assembly and disassembly for off-to-on fluorescence responsive live cell imaging.RSC advances · 2022Review
- Application of Design of Expert software for evaluating the influence of formulation variables on the encapsulation efficacy, drug content and particle size of PEO-PPO-PEO/Poly (DL-lactide-co-caprolactone) nanoparticles as carriers for SN-38.Medicine and pharmacy reports · 2021Article
- Dual Color Imaging from a Single BFInternational journal of medical sciences · 2021Article
- Multi-mode biodegradable tumour-microenvironment sensitive nanoparticles for targeted breast cancer imaging.Nanoscale research letters · 2020Article
- Dual-Mode Contrast Agents with RGD-Modified Polymer for Tumour-Targeted US/NIRF Imaging.OncoTargets and therapy · 2020Article
- An EPR Strategy for Bio-responsive Fluorescence Guided Surgery with Simulation of the Benefit for Imaging.Theranostics · 2020Article
- RGD conjugated cell uptake off to on responsive NIR-AZA fluorophores: applications toward intraoperative fluorescence guided surgery.Chemical science · 2019Article
- NIR-II nanoprobes in-vivo assembly to improve image-guided surgery for metastatic ovarian cancer.Nature communications · 2018Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Directed self-assemblies in water are known as the most efficient means of forming complex higher ordered structures in nature. Here we show a straightforward and robust method for particle assembly which utilises the amphiphilic tri-block co-polymer poloxamer-188 and a hydrophobic fluorophore as the two designer components, which have a built-in ability to convey spatial and temporal information about their surroundings to an observer. Templating of particle self-assembly is attributed to interactions between the fluorophore and hydrophobic segment of the poloxamer. Particle fluorescence in water is quenched but can be induced to selectively switch on in response to temperature, surface adsorption and cellular uptake. The ability of the particles to dynamically modulate emission intensity can be exploited for selective labelling and real-time imaging of drug crystal surfaces, natural fibres and insulin fibrils, and cellular delivery. As particle solutions are easily prepared, further applications for this water-based NIR-fluorescent paint are anticipated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.