ArticleScientific reports2017
The importance of parameter choice in modelling dynamics of the eye lens.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Ciliary Zonule of the Human Eye: Structural and Mechanical Aspects.Investigative ophthalmology & visual science · 2026Article
- Age-Related Changes in Lens Elasticity Contribute More to Accommodative Decline Than Shape Change.Investigative ophthalmology & visual science · 2025Article
- Effect of intraocular pressure on crystalline lens oscillations: a computational study using porcine eye model.PloS one · 2025Article
- Investigation of crystalline lens overshooting:Frontiers in bioengineering and biotechnology · 2024Article
- Estimation of Crystalline Lens Material Properties From Patient Accommodation Data and Finite Element Models.Investigative ophthalmology & visual science · 2023Article
- Seeing the future: Predictive control in neural models of ocular accommodation.Journal of vision · 2022Article
- 3D Modeling of the Crystalline Lens Complex under Pseudoexfoliation.Bioengineering (Basel, Switzerland) · 2022Article
- A numerical investigation of changes in lens shape during accommodation.Scientific reports · 2021Article
- The effects of mechanical strain on mouse eye lens capsule and cellular microstructure.Molecular biology of the cell · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The lens provides refractive power to the eye and is capable of altering ocular focus in response to visual demand. This capacity diminishes with age. Current biomedical technologies, which seek to design an implant lens capable of replicating the function of the biological lens, are unable as yet to provide such an implant with the requisite optical quality or ability to change the focussing power of the eye. This is because the mechanism of altering focus, termed accommodation, is not fully understood and seemingly conflicting theories require experimental support which is difficult to obtain from the living eye. This investigation presents finite element models of the eye lens based on data from human lenses aged 16 and 35 years that consider the influence of various modelling parameters, including material properties, a wide range of angles of force application and capsular thickness. Results from axisymmetric models show that the anterior and posterior zonules may have a greater impact on shape change than the equatorial zonule and that choice of capsular thickness values can influence the results from modelled simulations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.