Evidence map›Paper›PMID 29191927›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2018

Associations Between Residential Proximity to Traffic and Vascular Disease in a Cardiac Catheterization Cohort.

Cavin K Ward-Caviness, William E Kraus, Colette Blach, Carol S Haynes, Elaine Dowdy, Marie Lynn Miranda, Robert Devlin, David Diaz-Sanchez, Wayne E Cascio, Shaibal Mukerjee and 6 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Evaluation of PMEnvironmental epidemiology (Philadelphia, Pa.) · 2021
    Article
  9. Article
  10. Article
  11. Review
  12. Neighborhood sociodemographic effects on the associations between long-term PMEnvironmental epidemiology (Philadelphia, Pa.) · 2019
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Cavin K Ward-CavinessFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.). ward-caviness.cavin@epa.gov.
William E KrausFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Colette BlachFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Carol S HaynesFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Elaine DowdyFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Marie Lynn MirandaFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Robert DevlinFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
David Diaz-SanchezFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Wayne E CascioFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Shaibal MukerjeeFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Casson StallingsFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Luther A SmithFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Simon G GregoryFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Svati H ShahFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Lucas M NeasFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Elizabeth R HauserFrom the National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C., R.D., D.D.-S., W.E.C., L.M.N.); Duke Molecular Physiology Institute, Durham, NC (W.E.K., C.B., C.S.H., E.D., S.G.G., S.H.S., E.R.H.); Division of Cardiology, Duke University School of Medicine, Durham, NC (W.E.K., S.H.S.); Department of Statistics, Rice University, Houston, TX (M.L.M.); National Exposure Research Laboratory, US Environmental Protection Agency, Research Triangle Park, NC (S.M.); Metabolon, Research Triangle Park, NC (C.S.); Alion Science and Technology, Inc., Research Triangle Park, NC (L.A.S.); and Epidemiologic Research and Information Center, Durham Veterans, Affairs Medical Center, NC (E.R.H.).
Triangle · USAlion Science and Technology (United States) · USResearch Triangle Park Foundation · USDuke University · USMetabolon (United States) · USEnvironmental Protection Agency · USRice University · US

Funding

The Genetics Of Biobehavioral Risk Factors For CVDP01HL036587 · NHLBI · DUKE UNIVERSITY · PI KRAUS, WILLIAM E · 1986 to 2020
$35.9M
SNP discoveryP01HL073042 · NHLBI · DUKE UNIVERSITY · PI NEVINS, JOSEPH R · 2002 to 2006
$13.5M
Metabolomic Quantitative Trait Locus (mQTL) Genetic Mapping in Human CVDR01HL095987 · NHLBI · DUKE UNIVERSITY · PI SHAH, SVATI H. · 2009 to 2013
$3.4M
Intramural EPA EPA999999NHLBI NIH HHS P01 HL036587NHLBI NIH HHS P01 HL073042NHLBI NIH HHS R01 HL095987
6 · The paper itself

Abstract

objectiveExposure to mobile source emissions is nearly ubiquitous in developed nations and is associated with multiple adverse health outcomes. There is an ongoing need to understand the specificity of traffic exposure associations with vascular outcomes, particularly in individuals with cardiovascular disease. APPROACH AND

resultsWe performed a cross-sectional study using 2124 individuals residing in North Carolina, United States, who received a cardiac catheterization at the Duke University Medical Center. Traffic-related exposure was assessed via 2 metrics: (1) the distance between the primary residence and the nearest major roadway; and (2) location of the primary residence in regions defined based on local traffic patterns. We examined 4 cardiovascular disease outcomes: hypertension, peripheral arterial disease, the number of diseased coronary vessels, and recent myocardial infarction. Statistical models were adjusted for race, sex, smoking, type 2 diabetes mellitus, body mass index, hyperlipidemia, and home value. Results are expressed in terms of the odds ratio (OR). A 23% decrease in residential distance to major roadways was associated with higher prevalence of peripheral arterial disease (OR=1.29; 95% confidence interval, 1.08-1.55) and hypertension (OR=1.15; 95% confidence interval, 1.01-1.31). Associations with peripheral arterial disease were strongest in men (OR=1.42; 95% confidence interval, 1.17-1.74) while associations with hypertension were strongest in women (OR=1.21; 95% confidence interval, 0.99-1.49). Neither myocardial infarction nor the number of diseased coronary vessels were associated with traffic exposure.

conclusionsTraffic-related exposure is associated with peripheral arterial disease and hypertension while no associations are observed for 2 coronary-specific vascular outcomes.

Indexed as

Cardiac CatheterizationResidence CharacteristicsCoronary Artery DiseaseCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedMyocardial InfarctionNorth CarolinaPeripheral Arterial DiseasePrevalenceRisk AssessmentRisk FactorsTraffic-Related Pollutionair pollutionhypertensionmyocardial infarctionperipheral arterial diseasevascular diseases

Identifiers

PMID29191927
PMCPMC5972827
OpenAlexW2775464006

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.