Evidence map›Paper›PMID 29191925›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2018

Inhalation of Fine Particulate Matter Impairs Endothelial Progenitor Cell Function Via Pulmonary Oxidative Stress.

Petra Haberzettl, Daniel J Conklin, Wesley T Abplanalp, Aruni Bhatnagar, Timothy E O'Toole

Open access · bronzeAbstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Long-Term PMJournal of the American Heart Association · 2021
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Senolytics Reverse PMCardiovascular toxicology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Fine particulate matter (PMThe Science of the total environment · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Pollution and coronary risk: how much does it matter?European heart journal supplements : journal of the European Society of Cardiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Petra HaberzettlFrom the Department of Medicine, Diabetes and Obesity Center, Institute of Molecular Cardiology, University of Louisville, KY.
Daniel J ConklinFrom the Department of Medicine, Diabetes and Obesity Center, Institute of Molecular Cardiology, University of Louisville, KY.
Wesley T AbplanalpFrom the Department of Medicine, Diabetes and Obesity Center, Institute of Molecular Cardiology, University of Louisville, KY.
Aruni BhatnagarFrom the Department of Medicine, Diabetes and Obesity Center, Institute of Molecular Cardiology, University of Louisville, KY.
Timothy E O'TooleFrom the Department of Medicine, Diabetes and Obesity Center, Institute of Molecular Cardiology, University of Louisville, KY. tim.otoole@louisville.edu.
University of Louisville · US

Funding

Project 5 - Metabolomic Analysis of AtherothrombosisP20GM103492 · NIGMS · UNIVERSITY OF LOUISVILLE · PI HONG, KYUNG UK · 2012 to 2017
$13.8M
TBDP30GM127607 · NIGMS · UNIVERSITY OF LOUISVILLE · PI BHATNAGAR, ARUNI · 2018 to 2022
$6.3M
Endothelial Progenitor Cells and Particulate Air PollutionR01ES019217 · NIEHS · UNIVERSITY OF LOUISVILLE · PI BHATNAGAR, ARUNI, O'TOOLE, TIMOTHY E · 2011 to 2022
$6.0M
NIEHS NIH HHS R01 ES019217NIGMS NIH HHS P20 GM103492NIGMS NIH HHS P30 GM127607
6 · The paper itself

Abstract

objectiveExposure to fine particulate matter (PM APPROACH AND

resultsIn comparison with EPCs isolated from mice breathing filtered air, EPCs from mice exposed for 9 consecutive days (6 hours per day) to concentrated ambient PM

conclusionsExposure to PM

Indexed as

AnimalsCell MovementCell ProliferationCells, CulturedDisease Models, AnimalEndothelial Progenitor CellsHindlimbInhalation ExposureIschemiaLungMaleMice, Inbred C57BLMice, TransgenicMuscle, SkeletalNeovascularization, PhysiologicNitric OxideNitric OxideNitric Oxide Synthase Type IIINos3 protein, mouseParticulate MatterSuperoxide DismutaseVascular Endothelial Growth Factor Aair pollutionendothelial progenitor cellshind limb ischemiamiceparticulate matter

Identifiers

PMID29191925
PMCPMC5746456
OpenAlexW2772387492

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.