Evidence map›Paper›PMID 29191922›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2018

Adventitial Sca1+ Cells Transduced With ETV2 Are Committed to the Endothelial Fate and Improve Vascular Remodeling After Injury.

Alexandra Le Bras, Baoqi Yu, Shirin Issa Bhaloo, Xuechong Hong, Zhongyi Zhang, Yanhua Hu, Qingbo Xu

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Resident vascular Sca1iScience · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Vascular Stem/Progenitor Cells in Vessel Injury and Repair.Frontiers in cardiovascular medicine · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Annual Report on Sex in Preclinical Studies:Arteriosclerosis, thrombosis, and vascular biology · 2020
    Review
  15. Article
  16. Article
  17. Vascular progenitor cell senescence in patients with Marfan syndrome.Journal of cellular and molecular medicine · 2019
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alexandra Le BrasFrom the School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, United Kingdom.
Baoqi YuFrom the School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, United Kingdom.
Shirin Issa BhalooFrom the School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, United Kingdom.
Xuechong HongFrom the School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, United Kingdom.
Zhongyi ZhangFrom the School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, United Kingdom.
Yanhua HuFrom the School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, United Kingdom.
Qingbo XuFrom the School of Cardiovascular Medicine & Sciences, King's College London British Heart Foundation Centre, London, United Kingdom. qingbo.xu@kcl.ac.uk yanhua.hu@kcl.ac.uk.
British Heart Foundation · GB

Funding

British Heart Foundation RG/14/6/31144
6 · The paper itself

Abstract

objectiveVascular adventitial Sca1 APPROACH AND

resultsWe thus developed a fast, reproducible protocol based on the single-gene transfer of ETV2 (ETS variant 2) to differentiate Sca1

conclusionsThese data give evidence that the genetic manipulation of vascular progenitors is a promising approach to improve vascular function after endothelial injury.

Indexed as

Cell DifferentiationCell LineageTransduction, GeneticVascular RemodelingAdventitiaAnimalsAtaxin-1BiomarkersCells, CulturedDisease Models, AnimalEndothelial Progenitor CellsEpigenesis, GeneticFemoral ArteryGene Expression RegulationGenetic TherapyHyperplasiaAtaxin-1Atxn1 protein, mouseBiomarkersTranscription Factorsadventitiacell differentiationstem cellsvascular diseasesvascular remodeling

Identifiers

PMID29191922
PMCPMC5757665
OpenAlexW2773507916

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.