Evidence map›Paper›PMID 29191913›Full record

ArticleThe Journal of experimental medicine2018

Metabolic reprogramming of human CD8

Mark Y Jeng, Philip A Hull, Mingjian Fei, Hye-Sook Kwon, Chia-Lin Tsou, Herb Kasler, Che-Ping Ng, David E Gordon, Jeffrey Johnson, Nevan Krogan and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 110 citations in OpenAlex.

  1. Review
  2. Nicotinamide riboside enhances adoptive T cell therapy by promoting memory differentiation and metabolic fitness.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Post-translational modifications in CD8Frontiers in immunology · 2026
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Potential role of mesenchymal stem cells in T cell aging.Journal of molecular medicine (Berlin, Germany) · 2023
    Review

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Mark Y JengGladstone Institutes, San Francisco, CA.ORCID 0000-0003-0854-761X
Philip A HullGladstone Institutes, San Francisco, CA.ORCID 0000-0002-1176-6947
Mingjian FeiGladstone Institutes, San Francisco, CA.
Hye-Sook KwonGladstone Institutes, San Francisco, CA.
Chia-Lin TsouGladstone Institutes, San Francisco, CA.ORCID 0000-0002-1205-2970
Herb KaslerGladstone Institutes, San Francisco, CA.ORCID 0000-0002-6660-4267
Che-Ping NgGladstone Institutes, San Francisco, CA.
David E GordonGladstone Institutes, San Francisco, CA.
Jeffrey JohnsonGladstone Institutes, San Francisco, CA.
Nevan KroganGladstone Institutes, San Francisco, CA.
Eric VerdinGladstone Institutes, San Francisco, CA.
Melanie OttGladstone Institutes, San Francisco, CA mott@gladstone.ucsf.edu.ORCID 0000-0002-5697-1274
Gladstone Institutes · USQB3 · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
A new model of accelerated immune aging in HIV-infected drug usersDP1DA038043 · NIDA · J. DAVID GLADSTONE INSTITUTES · PI OTT, MELANIE MARIA · 2014 to 2019
$4.8M
BD FACSAria II Flow CytometerS10RR028962 · NCRR · J. DAVID GLADSTONE INSTITUTES · PI CAVROIS, MARIELLE · 2011 to 2011
$544k
NCRR NIH HHS S10 RR028962NIAID NIH HHS P30 AI027763NIDA NIH HHS DP1 DA038043
6 · The paper itself

Abstract

The expansion of CD8

Indexed as

Immunologic MemoryBiomarkersCD28 AntigensCD8-Positive T-LymphocytesCytotoxicity, ImmunologicEnergy MetabolismForkhead Box Protein O1Gene Expression RegulationHumansSirtuin 1T-Lymphocyte SubsetsBiomarkersCD28 AntigensForkhead Box Protein O1FOXO1 protein, humanSirtuin 1

Identifiers

PMID29191913
PMCPMC5748845
OpenAlexW2771883021

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.