Evidence map›Paper›PMID 2919175›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1989

Targeting of a chromosomal protein to the nucleus and to lampbrush chromosome loops.

M B Roth, J G Gall

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Localized co-transcriptional recruitment of the multifunctional RNA-binding protein CELF1 by lampbrush chromosome transcription units.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2007
    Article
  3. Lampbrush chromosomes and associated bodies: new insights into principles of nuclear structure and function.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2002
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

M B RothDepartment of Embryology, Carnegie Institution of Washington, Baltimore, MD 21210.
J G Gall
Carnegie Institution for Science · US

Funding

THE ORGANIZATION OF ANIMAL CELL NUCLEIR01GM033397 · NIGMS · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI GALL, JOSEPH G. · 1985 to 2019
$8.4M
THE ORGANIZATION OF ANIMAL CELL NUCLEIR37GM033397 · NIGMS · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI GALL, JOSEPH G. · 1990 to 1999
–
NIGMS NIH HHS GM 33397
6 · The paper itself

Abstract

We have isolated a cDNA clone (SE5A) that encodes a protein on lampbrush chromosome loops of the newt Notophthalmus. In vitro-synthesized transcripts of this clone were injected into Xenopus oocytes, where they were efficiently translated. Most of the translated protein was imported into the oocyte nucleus, and some of it appeared on the chromosome loops. The translation product must contain information that permits its appropriate targeting first to the nucleus and then to the chromosome loops.

Indexed as

Chromosome MappingGenesTranscription, GeneticAmino Acid SequenceAnimalsDNAFemaleMolecular Sequence DataNuclear ProteinsOocytesPlasmidsSalamandridaeXenopus laevisDNANuclear Proteins

Identifiers

PMID2919175
PMCPMC286669
OpenAlexW2011195962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.