ArticleThe American journal of cardiology2018
Histamine H
Registry-linked trialAbstract read
In one paragraph
Article in The American journal of cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03554291 (Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary Hypertension), which is not on this map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary Hypertension
Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Effect of Famotidine on Outcomes in Pulmonary Arterial Hypertension: A Randomized Controlled Trial.Chest · 2025Trial
- Does Cell-Type-Specific Silencing of Monoamine Oxidase B Interfere with the Development of Right Ventricle (RV) Hypertrophy or Right Ventricle Failure in Pulmonary Hypertension?International journal of molecular sciences · 2024Article
- Histamine H2 Receptor Antagonists in the Treatment and Prevention of Heart Failure.International journal of general medicine · 2024Review
- Associations of Histamine Metabolites with Disease Severity and Mortality in Pulmonary Arterial Hypertension.Annals of the American Thoracic Society · 2023Article
- Label-Free Investigations on the G Protein Dependent Signaling Pathways of Histamine Receptors.International journal of molecular sciences · 2021Article
- The Roles of Cardiovascular HFrontiers in pharmacology · 2021Review
- Boosting Akt Pathway by Rupatadine Modulates Th17/Tregs Balance for Attenuation of Isoproterenol-Induced Heart Failure in Rats.Frontiers in pharmacology · 2021Article
- Dynamic Regulation of SARS-Cov-2 Binding and Cell Entry Mechanisms in Remodeled Human Ventricular Myocardium.JACC. Basic to translational science · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 6 institutions in 1 country.
Peter J LearyDepartment of Medicine, University of Washington, Seattle, Washington. Electronic address: learyp@uw.edu.
Richard A KronmalDepartment of Biostatistics, University of Washington, Seattle, Washington.
David A BluemkeRadiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, Maryland.
Peter M ButtrickDepartment of Medicine, University of Colorado, Denver, Colorado.
Kenneth L JonesDepartment of Medicine, University of Colorado, Denver, Colorado.
David P KaoDepartment of Medicine, University of Colorado, Denver, Colorado.
Steven M KawutDepartments of Medicine and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Eric V KriegerDepartment of Medicine, University of Washington, Seattle, Washington.
Joao A LimaDepartment of Medicine, Johns Hopkins Hospital, Baltimore, Maryland; Department of Radiology, Johns Hopkins Hospital, Baltimore, Maryland.
Wayne MinobeDepartment of Medicine, University of Colorado, Denver, Colorado.
David D RalphDepartment of Medicine, University of Washington, Seattle, Washington.
Ryan J TedfordDepartment of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Noel S WeissDepartment of Epidemiology, University of Washington, Seattle, Washington.
Michael R BristowDepartment of Medicine, University of Colorado, Denver, Colorado.
University of Colorado Denver · USUniversity of Washington · USJohns Hopkins Hospital · USMedical University of South Carolina · USNational Institutes of Health Clinical Center · USUniversity of Pennsylvania · US
Funding
UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1MInstitute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1MTransgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PETER J TONTONOZ · 2003 to 2026
$40.4MWake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3MClinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2MNCCIH Supplement to NCATS/CTSA Program for KL2 Scholars - M. SoddersKL2TR002317 · NCATS · UNIVERSITY OF WASHINGTON · PI Christy Michelle McKinney · 2017 to 2026
$14.5MInstitute of Translational Health SciencesKL2TR000421 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$12.6MPOSTGRADUATE TRAINING IN CARDIOVASCULAR RESEARCHT32HL007822 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BUTTRICK, PETER N., LEINWAND, LESLIE ANNE · 1996 to 2023
$6.2MGenetic-Adrenergic Interactions in Myocardial FailureR01HL048013 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BRISTOW, MICHAEL R. · 1993 to 2007
$4.5MA Closed-Loop Integrated Framework for development of Novel Treatment Strategies in Heart Failure (CLIFFNOTES-HF)K08HL125725 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI KAO, DAVID PETER · 2017 to 2021
$826kSUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095166 · HC · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 1999 to 2001
$758kSUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC095162 · HC · JOHNS HOPKINS UNIVERSITY · PI SZKLO, MOYSES A · 1999 to 2000
$694kNCATS NIH HHS KL2 TR000421NCATS NIH HHS KL2 TR002317NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1 TR001881NHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS K08 HL125725NHLBI NIH HHS L30 HL110124NHLBI NIH HHS N01 HC065226NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL048013NHLBI NIH HHS R01 HL071118NHLBI NIH HHS T32 HL007822NIDDK NIH HHS P30 DK063491
Abstract
Myocardial H
Indexed as
Adrenergic beta-AntagonistsAgedAged, 80 and overAsianBlack or African AmericanCardiomyopathy, DilatedFemaleGene ExpressionGenetic Predisposition to DiseaseHeart FailureHispanic or LatinoHumansMaleMiddle AgedMyocardiumPharmacogenomic VariantsAdrenergic beta-AntagonistsReceptors, Histamine H2RNA, Messenger
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
NCT03554291ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.