Evidence map›Paper›PMID 29191291›Full record

ReviewSeminars in perinatology2017

Tocolysis: Present and future treatment options.

Joshua D Younger, Elena Reitman, George Gallos

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in perinatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

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  11. Differential Expression of CBCannabis and cannabinoid research · 2022
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  19. Functional comparison of anoctamin 1 antagonists on human uterine smooth muscle contractility and excitability.Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joshua D YoungerDepartment of Anesthesia, Columbia University Medical Center, New York, NY.
Elena ReitmanDepartment of Anesthesia, Columbia University Medical Center, New York, NY.
George GallosDepartment of Anesthesia, Columbia University Medical Center, New York, NY. Electronic address: gg2125@cumc.columbia.edu.
Columbia University Irving Medical Center · US

Funding

Calcium activated chloride channel modulation of myometrial excitabilityR01HD082251 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EMALA, CHARLES W · 2016 to 2020
$1.6M
NICHD NIH HHS R01 HD082251
6 · The paper itself

Abstract

In the United States, the generally accepted indication for tocolytic therapy centers on suppression of preterm labor. This may be in the form of preventative therapy with progesterone in women with prior spontaneous preterm birth or as an acute intervention to suppress established uterine contractions associated with cervical change occurring at less than 37 weeks gestation. This article seeks to apply this perspective to tocolytic therapy. Here, we provide a review of current tocolytic options and what the last decade of discovery has revealed about the regulation of myometrial excitability and quiescence. Moving forward, we must incorporate the emerging molecular data that is amassing in order to develop novel and effective tocolytic therapeutic options to prevent preterm labor and spontaneous preterm birth (sPTB).

Indexed as

AdultFemaleHumansObstetric Labor, PrematurePregnancyPremature BirthRandomized Controlled Trials as TopicTocolysisTocolytic AgentsTreatment OutcomeTocolytic AgentsPreterm birthPreterm laborTocolytics

Identifiers

PMID29191291
PMCPMC9363014
OpenAlexW2774189806

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.