ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2017
Optimized CEST cardiovascular magnetic resonance for assessment of metabolic activity in the heart.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed, 39 citations in OpenAlex.
- Ungated, plug-and-play preclinical cardiac CEST-MRI using radial FLASH with segmented saturation.Magnetic resonance in medicine · 2025Article
- Reliable Off-Resonance Correction in High-Field Cardiac MRI Using Autonomous Cardiac BBioengineering (Basel, Switzerland) · 2024Article
- Creatine mapping of the brain at 3T by CEST MRI.Magnetic resonance in medicine · 2024Article
- Biogenic Imaging Contrast Agents.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- Ketone ester supplementation suppresses cardiac inflammation and improves cardiac energetics in a swine model of acute myocardial infarction.Metabolism: clinical and experimental · 2023Article
- Mapping the Unseen: In Vivo CEST-MRI of Creatine Reveals Improved Cardiac Energetics in Subjects with Obesity Following Bariatric Surgery.Obesity surgery · 2023Article
- Creatine chemical exchange saturation transfer (CEST) CMR imaging reveals myocardial early involvement in idiopathic inflammatory myopathy at 3T: feasibility and initial experience.European radiology · 2023Article
- Label-Free Chemically and Molecularly Selective Magnetic Resonance Imaging.Chemical & biomedical imaging · 2023Review
- Magnetic resonance imaging of cardiac metabolism in heart failure: how far have we come?European heart journal. Cardiovascular Imaging · 2022Article
- Targeting Myocardial Substrate Metabolism in the Failing Heart: Ready for Prime Time?Current heart failure reports · 2022Review
- Radiomics and deep learning for myocardial scar screening in hypertrophic cardiomyopathy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022Article
- An end-to-end AI-based framework for automated discovery of rapid CEST/MT MRI acquisition protocols and molecular parameter quantification (AutoCEST).Magnetic resonance in medicine · 2022Article
- A Multimodal MR Imaging Study of the Effect of Hippocampal Damage on Affective and Cognitive Functions in a Rat Model of Chronic Exposure to a Plateau Environment.Neurochemical research · 2022Article
- Machine learning phenotyping of scarred myocardium from cine in hypertrophic cardiomyopathy.European heart journal. Cardiovascular Imaging · 2022Article
- Patient-specific apparent diffusion maps used to model nutrient availability in degenerated intervertebral discs.JOR spine · 2021Article
- CardiacHeart failure reviews · 2021Review
- Influence of phosphate concentration on amine, amide, and hydroxyl CEST contrast.Magnetic resonance in medicine · 2021Article
- Hybrid PET/MR imaging in myocardial inflammation post-myocardial infarction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Review
- Fast correction of BMagnetic resonance in medicine · 2020Article
- Journal of Cardiovascular Magnetic Resonance: 2017/2018 in review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPrevious studies have linked cardiac dysfunction to loss of metabolites in the creatine kinase system. Chemical exchange saturation transfer (CEST) is a promising metabolic cardiovascular magnetic resonance (CMR) imaging technique and has been applied in the heart for creatine mapping. However, current limitations include: (a) long scan time, (b) residual cardiac and respiratory motion, and (c) B
methodsAnimals with chronic myocardial infarction (N = 15) were scanned using the proposed CEST CMR technique and a late gadolinium enhancement (LGE) sequence as reference. The major improvements of the CEST CMR technique are: (a) Images were acquired by single-shot FLASH, significantly increasing the scan efficiency. (b) All images were registered to reduce the residual motion. (c) The acquired Z-spectrum was analyzed using 3-pool-model Lorentzian-line fitting to generate CEST signal, reducing the impact of B
resultsIn all animals, healthy remote myocardial CEST signal was elevated (0.16 ± 0.02) compared to infarct CEST signal (0.09 ± 0.02, P < 0.001) and the border zone (0.12 ± 0.02, P < 0.001). For both animal and patient studies, the hypointense regions in the CEST contrast maps closely match the bright areas in the LGE images.
conclusionsThe proposed CEST CMR technique was developed to address long scan times, respiratory and cardiac motion, and B
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.