Evidence map›Paper›PMID 29191165›Full record

ReviewBMC nephrology2017

Renal association clinical practice guideline on Anaemia of Chronic Kidney Disease.

Ashraf Mikhail, Christopher Brown, Jennifer Ann Williams, Vinod Mathrani, Rajesh Shrivastava, Jonathan Evans, Hayleigh Isaac, Sunil Bhandari

Registry-linked trialOpen access · goldAbstract readLetterReview
In one paragraph

Review in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05312346 (University Hospital), which is not on this map. Cited by 138 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 9 pooled it
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05312346 unknown statusnot on this mapstarted 2022, after this paper: background citation

University Hospital

TypeobservationalSponsorSohag UniversityRan2022 to 2023Enrolled50ConditionsPediatric Patients on HemodialysisArmsseum zinic,vit B12, parathyriod function
3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 9 syntheses or guidelines pooled it, 292 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Guideline
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2026
    Trial
  11. Trial
  12. Predictors of iron versus erythropoietin responsiveness in anemic hemodialysis patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2022
    Trial
  13. Randomized trial of sucrosomial iron supplementation in patients with chemotherapy-related anemia treated with ESA.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  14. Trial
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  17. Transcatheter or surgical aortic valve implantation in chronic dialysis patients: a German Aortic Valve Registry analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Trial
  18. Trial
  19. Article
  20. Article

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Ashraf MikhailAbertawe Bro Morgannwg University Health Board, Swansea, Wales, United Kingdom. melanie.dillon@renalregistry.nhs.uk.
Christopher BrownAbertawe Bro Morgannwg University Health Board, Swansea, Wales, United Kingdom.
Jennifer Ann WilliamsAbertawe Bro Morgannwg University Health Board, Swansea, Wales, United Kingdom.
Vinod MathraniAneurin Bevan University Health Board, Newport, Wales, United Kingdom.
Rajesh ShrivastavaAbertawe Bro Morgannwg University Health Board, Swansea, Wales, United Kingdom.
Jonathan EvansNottingham University Hospitals NHS Trust, Nottingham, England.
Hayleigh IsaacPatient Representative, c/o The Renal Association, Bristol, United Kingdom.
Sunil BhandariHull & East Yorkshire Hospitals NHS Trust, Hull, England.
Swansea Bay University Health Board · GBAneurin Bevan University Health Board · GBHull and East Yorkshire Hospitals NHS Trust · GBNottingham University Hospitals NHS Trust · GBRenal Association · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaemia is a commonly diagnosed complication among patients suffering with chronic kidney disease. If left untreated, it may affect patient quality of life. There are several causes for anaemia in this patient population. As the kidney function deteriorates, together with medications and dietary restrictions, patients may develop iron deficiency, resulting in reduction of iron supply to the bone marrow (which is the body organ responsible for the production of different blood elements). Chronic kidney disease patients may not be able to utilise their own body's iron stores effectively and hence, many patients, particularly those receiving haemodialysis, may require additional iron treatment, usually provided by infusion.With further weakening of kidney function, patients with chronic kidney disease may need additional treatment with a substance called erythropoietin which drives the bone marrow to produce its own blood. This substance, which is naturally produced by the kidneys, becomes relatively deficient in patients with chronic kidney disease. Any patients will eventually require treatment with erythropoietin or similar products that are given by injection.Over the last few years, several iron and erythropoietin products have been licensed for treating anaemia in chronic kidney disease patients. In addition, several publications discussed the benefits of each treatment and possible risks associated with long term treatment. The current guidelines provide advice to health care professionals on how to screen chronic kidney disease patients for anaemia, which patients to investigate for other causes of anaemia, when and how to treat patients with different medications, how to ensure safe prescribing of treatment and how to diagnose and manage complications associated with anaemia and the drugs used for its treatment.

Indexed as

AnemiaErythropoietinHumansPractice Guidelines as TopicRenal DialysisRenal Insufficiency, ChronicEPO protein, humanErythropoietin

Identifiers

PMID29191165
PMCPMC5709852
OpenAlexW2772547249

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.