Evidence map›Paper›PMID 29190974›Full record

ArticleOncotarget2017

MiR-3613-3p affects cell proliferation and cell cycle in hepatocellular carcinoma.

Donghui Zhang, Enqin Liu, Jian Kang, Xin Yang, Hong Liu

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Potential Regulation ofInternational journal of molecular sciences · 2025
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  9. Dynamic alternative polyadenylation during iPSC differentiation into cardiomyocytes.Computational and structural biotechnology journal · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Donghui ZhangDepartment of Infectious Disease, Linyi People's Hospital, Linyi 276000, China.
Enqin LiuDepartment of Infectious Disease, Linyi People's Hospital, Linyi 276000, China.
Jian KangDepartment of Colorectal Surgery, Tai'an City Central Hospital, Tai'an 271000, China.
Xin YangCulverhouse College of Commerce and Business Administration, The University of Alabama, Tuscaloosa, AL 35401, USA.
Hong LiuDepartment of Infectious Disease, Linyi People's Hospital, Linyi 276000, China.
Linyi People's Hospital · CNTaian City Central Hospital · CNUniversity of Alabama · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most common types of malignant tumors with poor sensitivity to chemotherapy drugs and poor prognosis among patients. In the present study, we downloaded the original data from the Gene Expression Omnibus and compared gene expression profiles of liver cancer cells in patients with HCC with those of colon epithelial cells of healthy controls to identify differentially expressed genes (DEGs). After filtering target microRNAs (miRNA) from core DEGs, we cultured HepG2 cells

Indexed as

cell cyclecell proliferationhepatocellular carcinomahsa-miR-3613-3p

Identifiers

PMID29190974
PMCPMC5696240
OpenAlexW2762684183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.