Evidence map›Paper›PMID 29190948›Full record

ArticleOncotarget2017

Enhanced antitumor efficacy and reduced toxicity of Abnormal Savda Munziq on tumor bearing mice treated with chemotherapy.

Tao Yang, Wenhui Shi, Zukereguli Wumaierniyazi, Lianlian Shan, Weiwei Miao, Guizhen Wu, Bin Zhou, Abdryim Yusup, Halmurat Upur, Ainiwaer Aikemu

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tao Yang *Department of Drug Analysis, Faculty of Pharmacy, Xinjiang Medical University, Urumqi 830011, China.
Wenhui Shi *Department of Animal Experiment, Urumqi General Hospital of Lanzhou Military, Urumqi 830011, China.
Zukereguli WumaierniyaziDepartment of Drug Analysis, Faculty of Pharmacy, Xinjiang Medical University, Urumqi 830011, China.
Lianlian ShanDepartment of Drug Analysis, Faculty of Pharmacy, Xinjiang Medical University, Urumqi 830011, China.
Weiwei MiaoDepartment of Drug Analysis, Faculty of Pharmacy, Xinjiang Medical University, Urumqi 830011, China.
Guizhen WuCentral Laboratory of Xinjiang Medical University, Urumqi 830011, China.
Bin ZhouDepartment of Drug Analysis, Faculty of Pharmacy, Xinjiang Medical University, Urumqi 830011, China.
Abdryim YusupTraditional Uighur Medicine and Pharmacology, Xinjiang Medical University, Urumqi 830011, China.
Halmurat UpurTraditional Uighur Medicine and Pharmacology, Xinjiang Medical University, Urumqi 830011, China.
Ainiwaer AikemuDepartment of Drug Analysis, Faculty of Pharmacy, Xinjiang Medical University, Urumqi 830011, China.
Xinjiang Medical University · CNUrumqi General Hospital of PLA · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous research has demonstrated the anti-tumor properties of Abnormal Savda Munziq (ASMq), a traditional Uyghur compound herbal medicine. The effects of ASMq on cervical carcinomas in U27 tumor-bearing mice is investigated, the effect of adding Fluorouracil (5-FU) is also assessed in this paper. The results demonstrate that ASMq and 5-FU significantly inhibited the proliferation of U27 cells in a time-dependent and dose-dependent manner. Evaluating the interactions between ASMq and 5-FU on U27 cell growth yields a combination index (CI) < 1 in different time periods, suggesting a synergistic effect between the two drugs

Indexed as

5-FUAbnormal Savda Munziqcervical cancer

Identifiers

PMID29190948
PMCPMC5696214
OpenAlexW2762160215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.