Evidence map›Paper›PMID 29190700›Full record

ArticlePloS one2017

Evaluation of the difference in caries experience in diabetic and non-diabetic children-A case control study.

Stefano Lai, Maria Grazia Cagetti, Fabio Cocco, Dina Cossellu, Gianfranco Meloni, Guglielmo Campus, Peter Lingström

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Stefano LaiDepartment of Biomedical Sciences, Medical School, University of Sassari, Sassari, Italy.
Maria Grazia CagettiWHO, Collaborating Centre for Epidemiology and Preventive Dentistry, Milan, Italy.
Fabio CoccoWHO, Collaborating Centre for Epidemiology and Preventive Dentistry, Milan, Italy.
Dina CosselluDepartment of Surgery, Microsurgery and Medical Sciences-Dental School, University of Sassari, Sassari, Italy.
Gianfranco MeloniDepartment of Surgery, Microsurgery and Medical Sciences-Clinic of Pediatric, University of Sassari, Sassari, Italy.
Guglielmo CampusWHO, Collaborating Centre for Epidemiology and Preventive Dentistry, Milan, Italy.ORCID http://orcid.org/0000-0002-8573-485X
Peter LingströmWHO, Collaborating Centre for Epidemiology and Preventive Dentistry, Milan, Italy.
University of Sassari · ITUniversity of Milan · ITWorld Health Organization - Italy · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the caries prevalence and related variables in Type 1 diabetic and non-diabetic children and among the diabetic children according to their metabolic status.

methodsSixty-eight diabetic and 136 non-diabetic children, matching by gender and age (4-14 years) were enrolled. The diabetic children were divided: a) 20 children in good metabolic control (Hb1ac≤7.5) and b) 48 children in bad metabolic control (Hb1ac>7.5). Dietary and oral hygiene habits were investigated. Caries status was registered using the International Caries Detection and Assessment System. Oral microflora was analysed using the checkerboard DNA-DNA hybridisation method. Plaque acidogenicity was recorded after a sucrose rinse.

resultsSugared beverage and snack intake was higher in diabetic group compared to non-diabetic group (p = 0.03 and p = 0.04, respectively) and in subjects in bad metabolic control (p = 0.03 and p<0.01, respectively). Oral hygiene habits were similar, except for the use of fluoridated adjuvants, higher in non-diabetic children (p = 0.04). No statistically significant differences were observed regarding caries figures, but a higher number of caries free subjects was found in diabetic subjects in good metabolic control (p<0.01). Significant difference for the main cariogenic bacteria was found between diabetic and non-diabetic subjects (p<0.05). The pH values showed statistically significant differences between diabetic and non-diabetic subjects and between diabetic subjects in good and bad metabolic control (p<0.01).

conclusionsDiabetic children in good metabolic control might even be considered at low caries risk, while those in bad metabolic control showed an oral environment prone to a high caries risk.

Indexed as

Diabetes ComplicationsAdolescentCase-Control StudiesChildChild, PreschoolDental CariesDental PlaqueFemaleHumansHydrogen-Ion ConcentrationMale

Identifiers

PMID29190700
PMCPMC5708823
OpenAlexW2771407255

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.