Observational studyAlzheimer's & dementia : the journal of the Alzheimer's Association2018
Clinical outcomes in older surgical patients with mild cognitive impairment.
Observational study in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06597812 (the Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium in Elderly Patient With Low Preoperative Mini-cog Score), which is not on this map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
the Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium in Elderly Patient With Low Preoperative Mini-cog Score
Who cites it
31 citing papers in PubMed, 61 citations in OpenAlex.
- Pre-Fracture Cognitive Assessment Using the DASC-21 and Postoperative Delirium Risk.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026Article
- From Acute Confusion to Chronic Decline: The Cognitive Impact of Delirium in Older Adults.Rhode Island medical journal (2013) · 2025Review
- Article
- Cognitive Impairment is Common and Unrecognized in Vascular Surgery Patients.Annals of vascular surgery · 2025Observational
- Mild cognitive impairment and postsurgical pain in older adults: A call for research.Journal of clinical anesthesia · 2025Article
- Colorectal Surgery Outcomes and Healthcare Burden for Medicare Beneficiaries With Dementia.The Journal of surgical research · 2025Article
- Article
- Association of preoperative cognitive frailty with postoperative complications in older patients under general anesthesia: a prospective cohort study.BMC geriatrics · 2024Article
- The effect of two different modes of anaesthesia maintenance on postoperative delirium in elderly patient with low preoperative mini-cog score.BMC anesthesiology · 2024Observational
- Using Systems Engineering and Implementation Science to Design an Implementation Package for Preoperative Comprehensive Geriatric Assessment Among Older Adults Having Major Abdominal Surgery: Protocol for a 3-Phase Study.JMIR research protocols · 2024Article
- Cognitive function and ability to complete a web-based geriatric assessment among older adults with cancer.Journal of the American Geriatrics Society · 2024Article
- The Clock-Drawing Test as a Useful Screening Assessment of Preoperative Cognitive Impairment with Readmission After Transcatheter Aortic Valve Implantation.Yonago acta medica · 2023Article
- Outcomes for patients with dementia undergoing emergency and elective colorectal surgery: A large multi-institutional comparative cohort study.American journal of surgery · 2023Article
- Preoperative frailty vs. cognitive impairment: Which one matters most for postoperative delirium among older adults with cancer?Journal of geriatric oncology · 2023Article
- Preoperative Risk Factors Associated with Increased Incidence of Postoperative Delirium: Systematic Review of Qualified Clinical Studies.Geriatrics (Basel, Switzerland) · 2023Review
- Moderate-to-high risk of obstructive sleep apnea with excessive daytime sleepiness is associated with postoperative neurocognitive disorders: a prospective one-year follow-up cohort study.Frontiers in neuroscience · 2023Article
- Postoperative delirium is an independent factor influencing the length of stay of elderly patients in the intensive care unit and in hospital.Journal of anesthesia · 2022Observational
- A novel predictive strategy for the incidence of postoperative neurocognitive dysfunction in elderly patients with mild cognitive impairment.Frontiers in aging neuroscience · 2022Article
- Physical and Cognitive Function Assessment to Predict Postoperative Outcomes of Abdominal Surgery.The Journal of surgical research · 2021Article
- Machine Learning to Develop and Internally Validate a Predictive Model for Post-operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients.Journal of general internal medicine · 2021Observational
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
Abstract
introductionOlder adults, including those with mild cognitive impairment (MCI), are increasingly undergoing surgery.
methodsRelative risks (RRs) of MCI alone or with delirium on adverse outcomes were estimated in an ongoing prospective, observational cohort study of 560 nondemented adults aged ≥70 years.
resultsMCI (n = 61, 11%) was associated with increased RR of delirium (RR = 1.9, P < .001) and delirium severity (RR = 4.6, P < .001). Delirium alone (n = 107), but not MCI alone (n = 34), was associated with multiple adverse outcomes including more major postoperative complication(s) (RR = 2.5, P = .002) and longer length of stay (RR = 2.2, P < .001). Patients with concurrent MCI and delirium (n = 27) were more often discharged to a postacute facility (RR = 1.4, P < .001) and had synergistically increased risk for new impairments in cognitive functioning (RR = 3.6, P < .001). DISCUSSION: MCI is associated with increased risk of delirium incidence and severity. Patients with delirium and MCI have synergistically elevated risk of developing new difficulties in cognitively demanding tasks.
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