Evidence map›Paper›PMID 29190082›Full record

ArticleJournal of the American Chemical Society2018

Pourbaix Diagram, Proton-Coupled Electron Transfer, and Decay Kinetics of a Protein Tryptophan Radical: Comparing the Redox Properties of W

Starla D Glover, Robin Tyburski, Li Liang, Cecilia Tommos, Leif Hammarström

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Conformationally gated multisite proton-coupled electron transfer in the ribonucleotide reductaseProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Hydrogen production by a fullyDalton transactions (Cambridge, England : 2003) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Oxalate decarboxylase uses electron hole hopping for catalysis.The Journal of biological chemistry · 2021
    Article
  12. Article
  13. Article
  14. Proton-Coupled Electron Transfer from Tyrosine in the Interior of aJournal of the American Chemical Society · 2020
    Article
  15. Article
  16. Article
  17. Direct Measurement of Charge Regulation in Metalloprotein Electron Transfer.Angewandte Chemie (International ed. in English) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Starla D GloverDepartment of Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine , Philadelphia, Pennsylvania 19104, United States.
Robin TyburskiDepartment of Chemistry, Ångström Laboratory, Uppsala University , Box 523, SE-75120 Uppsala, Sweden.
Li LiangDepartment of Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine , Philadelphia, Pennsylvania 19104, United States.
Cecilia TommosDepartment of Biochemistry and Biophysics, University of Pennsylvania Perelman School of Medicine , Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0001-8095-8873
Leif HammarströmDepartment of Chemistry, Ångström Laboratory, Uppsala University , Box 523, SE-75120 Uppsala, Sweden.ORCID 0000-0002-9933-9084
Uppsala University · SEUniversity of Pennsylvania · US

Funding

Understanding Protein RadicalsR01GM079190 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI TOMMOS, CECILIA · 2008 to 2024
$3.6M
NIGMS NIH HHS R01 GM079190
6 · The paper itself

Abstract

Protein-based "hole" hopping typically involves spatially arranged redox-active tryptophan or tyrosine residues. Thermodynamic information is scarce for this type of process. The well-structured α

Indexed as

ProtonsElectron TransportFree RadicalsKineticsOxidation-ReductionProteinsThermodynamicsTryptophanFree RadicalsProteinsProtonsTryptophan

Identifiers

PMID29190082
PMCPMC5762255
OpenAlexW2775056880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.