Evidence map›Paper›PMID 29190002›Full record

ArticleHead and neck pathology2018

Dentoalveolar Abscesses Not Associated with Caries or Trauma: A Diagnostic Hallmark of Hypophosphatemic Rickets Initially Misdiagnosed as Hypochondroplasia.

Silvia Elena Yacarini Paredes, Raquel Assed Bezerra Segato, Leila Daher Moreira, Alcides Moreira, Kranya Victoria Díaz Serrano, Clarissa Teles Rodrigues, Luciana Yamamoto Almeida, Jorge Esquiche León

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Head and neck pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Guideline
  2. Dental disease burden and management in children and young people with X-linked hypophosphataemia: a scoping review and service evaluation.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Silvia Elena Yacarini ParedesDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of Sao Paulo, São Paulo, SP, Brazil.
Raquel Assed Bezerra SegatoDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of Sao Paulo, São Paulo, SP, Brazil.
Leila Daher MoreiraDiagnóstico Bucal do Centro Universitário da Grande Dourados (UNIGRAN-MS), Dourados, Brazil.
Alcides MoreiraDiagnóstico Bucal do Centro Universitário da Grande Dourados (UNIGRAN-MS), Dourados, Brazil.
Kranya Victoria Díaz SerranoDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of Sao Paulo, São Paulo, SP, Brazil.
Clarissa Teles RodriguesDepartment of Dentistry, Endodontics and Dental Materials, School of Dentistry of Bauru, University of São Paulo, São Paulo, SP, Brazil.
Luciana Yamamoto AlmeidaHematology Division, Department of Clinical Medicine, Ribeirão Preto Medical School (FMRP/USP), University of São Paulo, São Paulo, SP, Brazil.
Jorge Esquiche LeónOral Pathology, Department of Stomatology, Public Oral Health, and Forensic Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, São Paulo, SP, Brazil. jleon@forp.usp.br.
Universidade de São Paulo · BRCentro Universitário da Grande Dourados · BR

Funding

Grants The São Paulo Research Foundation (FAPESP) 2011/52090-8Grants The São Paulo Research Foundation (FAPESP) 2016/11419-0
6 · The paper itself

Abstract

Hypophosphatemic rickets is a rare genetic disorder involving the regulation of fibroblast growth factor 23 (FGF23), a phosphaturic agent, clinically showing bowing of the legs, short stature and dentoalveolar abscesses. A 7-year-old boy, with previous hypochondroplasia diagnosis, was referred to our pediatric dentistry clinic presenting short stature, bone deformities and sinus tracts at deciduous teeth apex levels not related with trauma, restorations or dental caries. After deciduous teeth extraction, due to root resorption and mobility, light microscopy exhibited typical hypophosphatemic dentin, and micro-computed tomography revealed tubular clefts and porosities throughout the teeth. Laboratory tests confirmed the HR diagnosis, after which the treatment was initiated.

Indexed as

Bone and BonesChildDiagnostic ErrorsDwarfismFibroblast Growth Factor-23HumansLimb Deformities, CongenitalLordosisMalePeriapical AbscessRickets, HypophosphatemicFibroblast Growth Factor-23Dentoalveolar abscessesHypophosphatemic ricketsOral histopathologyOral manifestationsPediatric patientµ-CT

Identifiers

PMID29190002
PMCPMC6232211
OpenAlexW2771279063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.