ArticleInternational journal of clinical pharmacy2018
Validation of knowledge and adherence assessment tools among patients on warfarin therapy in a Saudi hospital anticoagulant clinic.
Article in International journal of clinical pharmacy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 7 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 7 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Quality of measurement properties of medication adherence instruments in cardiovascular diseases and type 2 diabetes mellitus: a systematic review and meta-analysis.Systematic reviews · 2023Pooled it
- Pooled it
- Measurement Properties of Patient-Reported Outcome Measures for Medication Adherence in Cardiovascular Disease: A COSMIN Systematic Review.Clinical drug investigation · 2022Pooled it
- Self-report instruments for assessing adherence to warfarin therapy: a systematic review.European journal of clinical pharmacology · 2021Pooled it
- A Systematic Review on Mobile Health Applications' Education Program for Patients Taking Oral Anticoagulants.International journal of environmental research and public health · 2021Pooled it
- Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Development of an Item Bank to Measure Medication Adherence: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Association between knowledge of anticoagulation, INR control, and warfarin-related adverse events: a cross sectional study.BMC research notes · 2025Observational
- Translation, cultural adaptation and validation of the General Medication Adherence Scale (GMAS) in moroccan patients with type-2 diabetes.BMC nursing · 2023Article
- Position Statement on In-hospital/Clinic Point-of-care Coagulation Testing for Anticoagulation Monitoring in Saudi Arabia.Journal of the Saudi Heart Association · 2023Article
- Medication Adherence and Health Literacy in Patients with Heart Failure: A Cross-Sectional Survey in Iran.Health literacy research and practice · 2022Article
- Warfarin Adherence Among Patients with Atrial Fibrillation in Rural Area of Dongyang, China: A Questionnaire-Based Study.Patient preference and adherence · 2022Article
- Validation of a Knowledge Test in Turkish Patients on Warfarin Therapy at an Ambulatory Anticoagulation ClinicTurkish journal of pharmaceutical sciences · 2021Article
- Impact of adherence to warfarin therapy during 12 weeks of pharmaceutical care in patients with poor time in the therapeutic range.Journal of thrombosis and thrombolysis · 2021Article
- The anti-clot treatment scale (ACTS): validation of the translated Arabic version among patients undergoing warfarin therapy in Saudi Arabia.Health and quality of life outcomes · 2020Article
- Validation of the General Medication Adherence Scale in Saudi Patients With Chronic Diseases.Frontiers in pharmacology · 2019Article
- Factors related to treatment adherence among hypertensive patients: A cross-sectional study in primary healthcare centers in Taif city.Journal of family & community medicineArticle
- Translation, Pilot Psychometric Validation, and Comparative Performance of the Arabic Version of the Anti-Clot Treatment Scale (ACTS).Journal of pharmacy & bioallied sciencesArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Although it can result in serious complications due to its narrow therapeutic index, warfarin is widely used in the treatment and prevention of thromboembolic disorders. However, patients' adherence and knowledge are determinants of therapeutic success. Objective We sought to validate instruments to provide a reliable means of identifying gaps in patient understanding and nonadherence to inform targeted pharmacists' interventions to improve these measures. Methods A cross-sectional survey was conducted. Patients' knowledge about warfarin was rated using an Arabic-language tool. Medication adherence was assessed using the eight-item Morisky Medication Adherence Scale (MMAS-8). The international normalized ratio (INR) control was quantified by the Rosendaal Method. Setting At the Security Forces hospital anticoagulant clinic (ACC), Riyadh. Main outcome measure Validity of a Knowledge and adherence tool. Results Totally, 101 patients completed the questionnaires. Interestingly, the knowledge tool demonstrated good internal consistency (total Cronbach's alpha = 0.75) and significant concurrent validity with adherence levels. Fifty-two patients were classified as having unsatisfactory knowledge. Deficiency in knowledge was most obvious with respect to the consequences of missing a dose and when to seek immediate medical attention. The MMAS-8 had moderate reliability (Cronbach's alpha = 0.65); however, its concurrent validity with good INR control was not demonstrated. Conclusions This study revealed high prevalence of nonadherence and poor knowledge in the population visiting the ACC. Given that available knowledge and adherence tools seemed to have little validity in predicting clinical outcomes, structured tools should be designed, considering progression in clinical outcomes with future pharmacists' interventions.
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