Evidence map›Paper›PMID 29189954›Full record

ArticleChemistry Central journal2017

Synthesis, anti-angiogenic and DNA cleavage studies of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)piperidine-4-carboxamide derivatives.

Vinaya Kambappa, G K Chandrashekara, N D Rekha, Prasanna D Shivaramu, Komaraiah Palle

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry Central journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. A Review on Medicinal Approaches of Novel Imatinib Derivatives.Current topics in medicinal chemistry · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Vinaya KambappaDepartment of Chemistry, Government First Grade College, Kadur, 577 548, India. vinaymphally@gmail.com.
G K ChandrashekaraDepartment of Chemistry, Government First Grade College, Kadur, 577 548, India.
N D RekhaDepartment of Studies in Biotechnology, JSS College of Arts, Commerce & Science, Ooty Road, Mysore, 570 025, India.
Prasanna D ShivaramuDepartment of Nanotechnology, Visvesvaraya Technological University, Center for Postgraduate Studies, Bengaluru Region, Muddenahalli, Ckikkaballapur, 562 101, India.
Komaraiah PalleDepartment of Oncological Sciences, Mitchell Cancer Institute, USA Mitchell Cancer Institute, 1660 Springhill Avenue, Mobile, AL, 36604, USA.
JSS Academy of Higher Education and Research · INUSA Mitchell Cancer Institute · USVisvesvaraya Technological University · IN

Funding

University Grants Commission 39-810⁄2010 (SR)
6 · The paper itself

Abstract

A series of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)piperidine-4-carboxamide derivatives 10(a-f), 12(a-c) and 14(a-c) were synthesized and characterized by FTIR,

Indexed as

3-acetylpyridineAntiangiogenic activityCAM assayDNA cleavage activityN-methyl morpholinePyrimidine

Identifiers

PMID29189954
PMCPMC5709256
OpenAlexW2772278830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.