Evidence map›Paper›PMID 29189759›Full record

ArticleBiosensors2017

Study of SH-SY5Y Cancer Cell Response to Treatment with Polyphenol Extracts Using FT-IR Spectroscopy.

Valerio Ricciardi, Marianna Portaccio, Simona Piccolella, Lorenzo Manti, Severina Pacifico, Maria Lepore

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  5. Differential Radiomodulating Action ofAntioxidants (Basel, Switzerland) · 2022
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Valerio RicciardiDipartimento di Fisica "Ettore Pancini", Università di Napoli "Federico II", 80126 Napoli, Italy. val.ricciardi89@gmail.com.
Marianna PortaccioDipartimento di Medicina Sperimentale, Università della Campania "Luigi Vanvitelli", 80138 Napoli, Italy. marianna.portaccio@unicampania.it.ORCID 0000-0003-4463-0779
Simona PiccolellaDipartimento di Scienze e Tecnologie Ambientali Biologiche e Farmaceutiche, Università della Campania "Luigi Vanvitelli", 81100 Caserta, Italy. simona.piccolella@unicampania.it.
Lorenzo MantiDipartimento di Fisica "Ettore Pancini", Università di Napoli "Federico II", 80126 Napoli, Italy. lorenzo.manti@na.infn.it.
Severina PacificoDipartimento di Scienze e Tecnologie Ambientali Biologiche e Farmaceutiche, Università della Campania "Luigi Vanvitelli", 81100 Caserta, Italy. severina.pacifico@unicampania.it.
Maria LeporeDipartimento di Medicina Sperimentale, Università della Campania "Luigi Vanvitelli", 80138 Napoli, Italy. maria.lepore@unicampania.it.ORCID 0000-0003-2743-5904
University of Campania "Luigi Vanvitelli" · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant polyphenols are important components of human diet and a number of them are considered to possess chemo-preventive and therapeutic properties against cancer. They are recognized as naturally occurring antioxidants, but also as pro-oxidant, pro-apoptotic, or chromosomal aberrations inducers, depending on their concentration and/or the stage of cell-cycle of the cells with which they interact. For these reasons, particular interest is devoted to knowing the total effects of polyphenols on the cell cycle and metabolism. Fourier-Transform Infrared (FT-IR) spectroscopy thanks to its ability in analyzing cells at a molecular level can be particularly useful in investigating the biochemical changes induced in protein, nucleic acid, lipid, and carbohydrate content of cells by means of polyphenols administration. Spectroscopic analysis was performed on

Indexed as

Spectroscopy, Fourier Transform InfraredBiomarkersCell Line, TumorDose-Response Relationship, DrugHumansPlant ExtractsPolyphenolsTime FactorsBiomarkersPlant ExtractsPolyphenolscells-polyphenols interactionFourier-Transform Infrared microspectroscopyneuroblastoma cellsplant polyphenols

Identifiers

PMID29189759
PMCPMC5746780
OpenAlexW2772299621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.