ArticleThe Pediatric infectious disease journal2018
Race, Income and Insurance Status Affect Neonatal Sepsis Mortality and Healthcare Resource Utilization.
Article in The Pediatric infectious disease journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Socioeconomic disparities in the postnatal growth of preterm infants: a systematic review.Pediatric research · 2025Pooled it
- Rapid systematic review on risks and outcomes of sepsis: the influence of risk factors associated with health inequalities.International journal for equity in health · 2024Pooled it
- Contemporary Trends in Global Mortality of Sepsis Among Young Infants Less Than 90 Days: A Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2022Pooled it
- The effect of exchange transfusion on mortality in neonatal sepsis: a meta-analysis.European journal of pediatrics · 2022Pooled it
- Evaluation of Bovine Lactoferrin for Prevention of Late-Onset Sepsis in Low-Birth-Weight Infants: A Double-Blind Randomized Controlled Trial.Nutrients · 2025Trial
- Exploring Social and Demographic Factors as Determinants of Intestinal Inflammation in Very Low Birth-Weight Infants.Advances in neonatal care : official journal of the National Association of Neonatal Nurses · 2021Trial
- Effect of probable neonatal sepsis on the development of infants in Eastern Uganda (ENON): a cohort study.BMJ paediatrics open · 2026Article
- The fetal exposome: cellular and epigenetic programming of neonatal immune function.Frontiers in immunology · 2026Review
- Autopsy-related histomorphological findings in neonatal sepsis: a narrative review.Forensic science, medicine, and pathology · 2025Review
- The Relationship Between Blood Culture, C-reactive Protein, and Neonatal Sepsis: A Cross-Sectional Study.Cureus · 2024Article
- Racial and ethnic inequities in the quality of paediatric care in the USA: a review of quantitative evidence.The Lancet. Child & adolescent health · 2024Review
- Treatment outcomes and its associated factors among neonates admitted with sepsis in Hiwot Fana Comprehensive Specialized University Hospital, Harar, Ethiopia.Frontiers in pediatrics · 2024Article
- Investigating Racial and Socioeconomic Characteristics in Pediatric Sepsis Using Electronic Health Data.Hospital pediatrics · 2023Article
- Disparities Associated with Sepsis Mortality in Critically Ill Children.Journal of pediatric intensive care · 2022Article
- Neonatal sepsis and mortality in low-income and middle-income countries from a facility-based birth cohort: an international multisite prospective observational study.The Lancet. Global health · 2022Observational
- Article
- Hospital outcomes for children with severe sepsis in the USA by race or ethnicity and insurance status: a population-based, retrospective cohort study.The Lancet. Child & adolescent health · 2021Article
- Stressors and support system among parents of neonates hospitalised with systemic infections: qualitative study in South India.Archives of disease in childhood · 2021Article
- Challenges in developing a consensus definition of neonatal sepsis.Pediatric research · 2020Review
- Interfacility Transfers Among Patients With Complex Chronic Conditions.Hospital pediatrics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundSocioeconomic disparities negatively impact neonatal health. The influence of sociodemographic disparities on neonatal sepsis is understudied. We examined the association of insurance payer status, income, race and gender on neonatal sepsis mortality and healthcare resource utilization.
methodsWe used the Kid's Inpatient Database, a nationwide population-based survey from 2006, 2009 and 2012. Neonates diagnosed with sepsis were included in the study. Multivariable logistic regression (mortality) and multivariable linear regression (length of stay and total hospital costs) were constructed to determine the association of patient and hospital characteristics.
resultsOur study cohort included a weighted sample of 160,677 septic neonates. Several sociodemographic disparities significantly increased mortality. Self-pay patients had increased mortality (odds ratio 3.26 [95% confidence interval: 2.60-4.08]), decreased length of stay (-2.49 ± 0.31 days, P < 0.0001) and total cost (-$5015.50 ± 783.15, P < 0.0001) compared with privately insured neonates. Additionally, low household income increased odds of death compared with the most affluent households (odds ratio 1.19 [95% confidence interval: 1.05-1.35]). Moreover, Black neonates had significantly decreased length of stay (-0.86 ± 0.25, P = 0.0005) compared with White neonates.
conclusionsThis study identified specific socioeconomic disparities that increased odds of death and increased healthcare resource utilization. Moreover, this study provides specific societal targets to address to reduce neonatal sepsis mortality in the United States.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.