ArticleClimacteric : the journal of the International Menopause Society2018
Pregnancy history, coronary artery calcification and bone mineral density in menopausal women.
Article in Climacteric : the journal of the International Menopause Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Subclinical atherosclerosis in women after pre-eclampsia: a systematic review and meta-analysis.Heart (British Cardiac Society) · 2026Pooled it
- Trabecular bone density in middle-aged women with reproductive disorders.Endocrine connections · 2023Article
- Article
- Preeclampsia and Fetal Growth Restriction as Risk Factors of Future Maternal Cardiovascular Disease-A Review.Journal of clinical medicine · 2022Review
- Current Updates on Pre-eclampsia: Maternal and Foetal Cardiovascular Diseases Predilection, Science or Myth? : Future cardiovascular disease risks in mother and child following pre-eclampsia.Current hypertension reports · 2021Review
- Participation of rural patients in clinical trials at a multisite academic medical center.Journal of clinical and translational science · 2021Article
- The Association of Adverse Pregnancy Outcomes and Cardiovascular Disease: Current Knowledge and Future Directions.Current treatment options in cardiovascular medicine · 2020Article
- Cross-sectional association of bone mineral density with coronary artery calcification in an international multi-ethnic population-based cohort of men aged 40-49: ERA JUMP study.International journal of cardiology. Heart & vasculature · 2020Article
- Inorganic Phosphate in the Pathogenesis of Pregnancy-Related Complications.International journal of molecular sciences · 2020Article
- Future risk of cardiovascular disease risk factors and events in women after a hypertensive disorder of pregnancy.Heart (British Cardiac Society) · 2019Review
- A Systematic Review of Vascular Structure and Function in Pre-eclampsia: Non-invasive Assessment and Mechanistic Links.Frontiers in cardiovascular medicine · 2019Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveThis study examined relationships, by pregnancy histories, between bone mineral density (BMD) and coronary artery calcification (CAC) in postmenopausal women.
methodsForty women identified from their medical record as having pre-eclampsia (PE) were age/parity-matched with 40 women having a normotensive pregnancy (NP). Vertebral (T4-9) BMD and CAC were assessed by quantitative computed tomography in 73 (37 with PE and 36 with NP) of the 80 women. Analyses included linear regression using generalized estimating equations.
resultsWomen averaged 59 years of age and 35 years from the index pregnancy. There were no significant differences in cortical, trabecular or central BMD between groups. CAC was significantly greater in the PE group (p = 0.026). In multivariable analysis, CAC was positively associated with cortical BMD (p = 0.001) and negatively associated with central BMD (p = 0.036). There was a borderline difference in the association between CAC and central BMD by pregnancy history (interaction, p = 0.057).
conclusionsAlthough CAC was greater in women with a history of PE, vertebral BMD did not differ between groups. However, both cortical and central BMD were associated with CAC. The central BMD association was marginally different by pregnancy history, suggesting perhaps differences in underlying mechanisms of soft tissue calcification.
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Registered trials
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