Evidence map›Paper›PMID 29188817›Full record

ArticleInternational journal of obesity (2005)2018

Dietary sugar intake was associated with increased body fatness but decreased cardiovascular mortality in Chinese elderly: an 11-year prospective study of Mr and Ms OS of Hong Kong.

Z-M Liu, L A Tse, D Chan, C Wong, S Y S Wong

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In one paragraph

Article in International journal of obesity (2005), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  8. Tolerable upper intake level for dietary sugars.EFSA journal. European Food Safety Authority · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Z-M LiuDepartment of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China.
L A TseDivision of Environmental and Occupational Health, Jockey Club School of Public Health and Primary Healthcare, the Chinese University of Hong Kong, Hong Kong, Hong Kong SAR.
D ChanDivision of Family Medicine and Primary Healthcare, Jockey Club School of Public Health and Primary Care, the Chinese University of Hong Kong, Hong Kong, Hong Kong SAR.
C WongDivision of Family Medicine and Primary Healthcare, Jockey Club School of Public Health and Primary Care, the Chinese University of Hong Kong, Hong Kong, Hong Kong SAR.
S Y S WongDivision of Family Medicine and Primary Healthcare, Jockey Club School of Public Health and Primary Care, the Chinese University of Hong Kong, Hong Kong, Hong Kong SAR.
Chinese University of Hong Kong · CNHong Kong Jockey Club · CNSun Yat-sen University · CN

Funding

Osteoporotic fractures in Chinese men: MrOs Hong KongR01AR049439 · NIAMS · CHINESE UNIVERSITY OF HONG KONG · PI LEUNG, PING CHUNG · 2003 to 2007
$2.0M
NIAMS NIH HHS R01 AR049439
6 · The paper itself

Abstract

BACKGROUND/

objectivesEpidemiological studies suggest that sugar intake contributes to weight gain and increased risk of cardiovascular diseases (CVDs). However, this association is largely undefined in the elderly population. Our aim was to investigate the effect of sugar consumption on the subsequent changes in body fatness and CVD mortality in Chinese elderly.

methodsA total of 2000 men and 2000 women aged ⩾65 years were recruited from 2001 to 2003. Dietary sugar intake was estimated based on a validated 329-item food frequency questionnaire and a local sugar database. Adiposity was measured using dual-energy X-ray absorptiometry at baseline and follow-up after 4 years. Mortality was ascertained by local death registry until March 2014. Multivariable linear and Cox regression were conducted to evaluate the association of sugar consumption on the changes in body fatness and CVD mortality.

resultsA total of 174 CVD deaths were documented within the total 37 999 person-years' follow-up. Significant positive association between sugar intake and increase in body fatness at follow-up after 4 years was found in men but not in women. After adjustment for potential confounders, men who consumed 1% increase in added sugar had an increase in whole body fat by 0.043 kg (P=0.006), central fat by 0.029 kg (P=0.016) and peripheral fat by 0.026 kg (P=0.006). However, in both genders, after an average of 11.1-year follow-up, compared with the lowest quintile, the highest intakes of added sugar were associated with significantly lowered CVD mortality by 74.9% (hazard ratio (HR) (95% confidence interval (CI)): 0.251(0.070, 0.899)) in a dose-response manner (P

conclusionsThus higher sugar intake of the Chinese elderly was associated with increased adiposity in men but decreased CVD mortality. The current World Health Organization recommendation for the elderly should be reviewed.

Indexed as

Dietary CarbohydratesAbsorptiometry, PhotonAdipose TissueAgedAsian PeopleCardiovascular DiseasesDietFemaleHong KongHumansMaleObesityOverweightProspective StudiesDietary Carbohydrates

Identifiers

PMID29188817
OpenAlexW2774183963

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.