ArticleAging clinical and experimental research2018
Trajectory and variability characterization of the Montreal cognitive assessment in older adults.
Article in Aging clinical and experimental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative efficacy of non-pharmacological interventions for amnestic mild cognitive impairment: a network meta-analysis.Frontiers in aging neuroscience · 2026Pooled it
- Trial
- Reliability and stability of cognitive intraindividual variability indices among cognitively unimpaired older adults.The Clinical neuropsychologist · 2026Article
- Longitudinal Associations between Cardiorespiratory Fitness and Cognition in Older Adults: A 10-Year Follow-Up from the Generation 100 Study.Medicine and science in sports and exercise · 2026Article
- Improving diagnostic accuracy of the Montreal Cognitive Assessment to identify post-stroke cognitive impairment.Scientific reports · 2024Observational
- Tau follows principal axes of functional and structural brain organization in Alzheimer's disease.Nature communications · 2024Article
- Feasibility and Efficacy of Online Neuropsychological Assessment.Sensors (Basel, Switzerland) · 2023Article
- Remote assessment of cognition in Parkinson's disease and Cerebellar Ataxia: the MoCA test in English and Hebrew.Frontiers in human neuroscience · 2023Article
- A Perspective: Challenges in Dementia Research.Medicina (Kaunas, Lithuania) · 2022Article
- Personality predictors of cognitive dispersion: A coordinated analysis of data from seven international studies of older adults.Neuropsychology · 2022Article
- Montreal Cognitive Assessment: Normative Data for Cognitively Healthy Swedish 80- to 94-Year-Olds.Journal of Alzheimer's disease : JAD · 2022Article
- Influence of Subject-Specific Effects in Longitudinal Modelling of Cognitive Decline in Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2022Article
- Use of coffee grounds to test olfaction for predicting cognitive dysfunction and decline.Journal of the neurological sciences · 2021Article
- Challenging the relationship of grip strength with cognitive status in older adults.International journal of geriatric psychiatry · 2021Article
- Longitudinal changes in MoCA performances in patients with mild cognitive impairment and small vessel disease. Results from the VMCI-Tuscany Study.Cerebral circulation - cognition and behavior · 2021Article
- Post-stroke cognitive impairments and responsiveness to motor rehabilitation: A review.Current physical medicine and rehabilitation reports · 2020Article
- Exploring the relationship between visuospatial function and age-related deficits in motor skill transfer.Aging clinical and experimental research · 2020Article
- Predicting motor skill learning in older adults using visuospatial performance.Journal of motor learning and development · 2020Article
- Cognitive Decline in Older Patients With Non- ST Elevation Acute Coronary Syndrome.Journal of the American Heart Association · 2019Article
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Authors and funding
5 authors.
Funding
Abstract
backgroundThe Montreal cognitive assessment (MoCA) has become one of the most widely used cognitive screening instruments since its initial publication. To date, only a handful of studies have explored longitudinal characteristics of the MoCA.
aimThe aim of this study is to characterize the trajectory of MoCA performance across a broad age continuum of older adults.
methodsData from 467 cognitively normal participants were used in this analysis. The sample was grouped into four strata based on the participants' age at baseline (60-69, 70-79, 80-89, and 90-99). Mixed model repeated measures (MMRM) analysis and mixed-effects spline models were used to characterize the trajectory of MoCA scores in each age stratum and in the entire sample. Intrasubject standard deviation (ISD) was used to characterize the natural variability of individual MoCA performance over time.
resultsThe ISD values for each of the age strata indicated that year-to-year individual variation on the MoCA ranged from zero to three points. MMRM analysis showed that the 60-69 stratum remained relatively stable over time while the 70-79 and 80-89 strata both showed notable decline relative to baseline performance. The mixed-effects spline model showed that MoCA performance declines linearly across the older adult age span. DISCUSSION: Among cognitively normal older adults MoCA performance remains relatively stable over time, however across the older adult age-span MoCA performance declines in a linear fashion. These results will help clinicians better understand the normal course of MoCA change in older adults while researchers may use these results to inform sample size estimates for intervention studies.
conclusionThis study provides an enhanced view of the MoCA's intraindividual trajectory in normal elderly aged 60 and older.
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