ReviewJournal of nephrology2018
A narrative review of the impact of interventions in acute kidney injury.
Review in Journal of nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Effect of acute kidney injury care bundle on kidney outcomes in cardiac patients receiving critical care: a systematic review and meta-analysis.BMC nephrology · 2025Pooled it
- Effect of care bundles for acute kidney injury: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Intermediate and long-term AKI outcomes in a public health system.Journal of nephrology · 2025Article
- Article
- What do older patients know about their medication? A cross-sectional, interview-based pilot study.European journal of clinical pharmacology · 2023Article
- Prediction of Postoperative Creatinine Levels by Artificial Intelligence after Partial Nephrectomy.Medicina (Kaunas, Lithuania) · 2023Article
- Impact of an Electronic Alert in Combination with a Care Bundle on the Outcomes of Acute Kidney Injury.Diagnostics (Basel, Switzerland) · 2022Article
- Clinical phenotypes of acute kidney injury are associated with unique outcomes in critically ill septic children.Pediatric research · 2021Observational
- Article
- Silence of Long Noncoding RNA SNHG14 Alleviates Ischemia/Reperfusion-Induced Acute Kidney Injury by Regulating miR-124-3p/MMP2 Axis.BioMed research international · 2021Article
- Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK/ULK1/autophagy pathway.Theranostics · 2021Article
- Development and Validation of a Nomogram for Predicting Drug-Induced Acute Kidney Injury in Hospitalized Patients: A Case-Control Study Based on Propensity-Score Matching.Frontiers in pharmacology · 2021Article
- AKI: an increasingly recognized risk factor for CKD development and progression.Journal of nephrology · 2020Review
- Calcitonin Gene-Related Peptide Attenuates LPS-Induced Acute Kidney Injury by Regulating Sirt1.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Preventing acute kidney injury and improving outcome in critically ill patients utilizing risk prediction score (PRAIOC-RISKS) study. A prospective controlled trial of AKI prevention.Journal of nephrology · 2020Article
- Validation by CT scan of quadriceps muscle thickness measurement by ultrasound in acute kidney injury.Journal of nephrology · 2020Observational
- Article
- Hypophosphatemia in critically ill patients with acute kidney injury on renal replacement therapies.Journal of nephrology · 2019Review
- Transitional care program to facilitate recovery following severe acute kidney injury.Journal of nephrology · 2019Article
- Angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker use prior to medical intensive care unit admission and in-hospital mortality: propensity score-matched cohort study.Journal of nephrology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute kidney injury (AKI) is independently associated with significant morbidity and mortality, and is thus an important challenge facing physicians in modern healthcare. This narrative review assesses the impact of strategies employed to tackle AKI following the 2009 NCEPOD report on acute kidney injury (Sterwart et al. Acute kidney injury: adding insult to injury, pp 1-22, 2009). There is scarce and heterogeneous research into hard end points such as mortality and AKI progression for AKI interventions. This review found that e-alerts have varying effects on mortality and AKI progression, but decrease the incidence of contrast-induced AKI. The use of AKI bundles delivers statistically significant improvements in mortality and AKI progression. Similarly, AKI nurses generate statistically significant improvements on hospital acquired AKI and mortality. As yet there is no evidence base for the effects of education, sick day rules and smart phone apps. Overall, a combination of e-alerts and AKI bundles supported by education yielded the most effective and statistically significant results. Current practice revolves around reactive rather than preventative behaviour. This narrative review discusses reactive interventions and their impact on the progression and severity of AKI, and on mortality from it. Preventative behaviour, such as risk stratification and early intervention in the deteriorating patient, may be influential in decreasing AKI incidence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.